Figure 1
From: GOLPH2 expression may serve as diagnostic marker in seminomas
GOLPH2 immunohistochemistry in testicular parenchyma and seminoma. In normal testicular tubules GOLPH2 is rather absent (A) or faintly expressed (B) in the germ cell lining of the tubules. Meanwhile the intertubular Leydig cells display a pronounced perinuclear GOLPH2 staining. In seminomas we observed weak (C), moderate (D/E) and strong (F) granular and perinuclear GOLPH2 stainings. The majority of the seminomas displayed the moderate intensity (D/E) expression pattern.