Figure 3
From: Quantification of HLA class I molecules on renal cell carcinoma using Edman degradation
Immunohistochemical staining of RCC377 tissues. Staining with the HLA class I specific antibody W6/32 demonstrates a higher expression of class I in tumor vs. benign kidney tissue. Expression in metastatic tissue is still higher. Although antigen presenting cells (APC) and endothelial cells contribute to HLA class I expression, tumor cells localized within this lymph node metastasis are also expressing class I at a high level.