Table 1 Tissue samples and amounts of immunopurified HLA class I
From: Quantification of HLA class I molecules on renal cell carcinoma using Edman degradation
Tissue specimen | Tumor (T) Normal renal tissue (NK) Metastasis (M) | Type | Mass (g) | TILs | Edman results (pmol) | Average HLA amount (pmol/g) |
|---|---|---|---|---|---|---|
RCC399 | NK T M (lymph node) | ccRCC | 2.4 13.8 1.0 | yes | 60 1000 40 | 25.0 72.5 40.0 |
RCC377 | NK T M (lymph node) | ccRCC | 4.2 12.7 4.5 | n.d | 500 6000 3500 | 119.0 472.4 777.8 |
RCC364 | NK T M (lymph node) | ccRCC | 1.2 5.8 0.4 | yes | 10 1000 20 | 8.3 172.4 50.0 |
Rcc343 | NK T M (liver) | ccRCC | 3.2 2.1 3.2 | n.d | 20 200 1400 | 6.3 95.2 437.5 |
RCC70 | NK T M (lymph node) | ccRCC | 4.4 8.3 2.6 | n.d. | 300 3200 200 | 68.2 385.5 76.9 |
RCC307 | NK T | pRCC | 2.7 1.6 | n.d. | 200 400 | 74.1 250.0 |
RCC211 | NK T | pRCC | 0.4 20.7 | n.d. | 10 2100 | 25.0 101.4 |
RCC193 | NK T | ccRCC | 2.4 4.7 | n.d. | 500 850 | 208.3 180.9 |
RCC131 | NK T | ccRCC | 6.5 11.5 | n.d. | 400 300 | 61.5 26.1 |
RCC121 | NK T | ccRCC | 6.2 10.4 | no | 500 460 | 44.2 80.6 |
RCC119 | NK T | ccRCC | 8.9 7.8 | yes | 440 560 | 49.4 71.8 |
RCC110 | NK T | chRCC | 13.0 7.0 | yes | 1700 3900 | 130.8 557.1 |
RCC100 | NK T | ccRCC | 12.6 8.0 | no | 1400 1200 | 111.1 150.0 |
RCC99 | NK T | ccRCC | 12.4 7.7 | no | 1500 1300 | 121.0 168.8 |
RCC81 | NK T | chRCC | 10.0 18.0 | no | 1400 1800 | 100.0 140.0 |
RCC76 | NK T | ccRCC | 6.2 12.8 | n.d. | 1200 2600 | 193.5 20.3 |
RCC71 | NK T | ccRCC | 9.0 7.0 | n.d. | 10 3000 | 1.1 428.6 |
RCC58 | NK T | ccRCC | 7.6 7.2 | no | 2000 2400 | 263.2 333.3 |
RCC57 | NK T | n.d. | 6.8 8.7 | yes | 1900 2500 | 279.4 287.4 |
RCC53 | NK T | n.d. | 6.9 6.2 | n.d. | 1300 1900 | 188.4 306.5 |
RCC52 | NK T | ccRCC | 7.4 7.0 | n.d. | 100 2000 | 13.5 285.7 |
RCC51 | NK T | chRCC | 7.0 7.8 | n.d. | 2100 2000 | 300.0 256.4 |
RCC49 | NK T | n.d. | 7.0 8.8 | n.d. | 1300 2900 | 185.7 329.5 |
RCC46 | NK T | n.d. | 7.6 9.3 | n.d. | 400 1500 | 52.6 161.3 |
RCC173 | NK M (contralateral k.) | ccRCC | 5,0 5,1 | n.d. | 40 240 | 8.0 47.1 |
RCC249 | T | chRCC | 2.6 | n.d. | 80 | 30.8 |
RCC231 | T | pRCC | 6.3 | n.d. | 380 | 60.3 |
RCC226 | T | ccRCC | 6.8 | n.d. | 250 | 36.8 |
RCC195 | T | ccRCC | 60.0 | n.d. | 50 | 0.8 |
RCC130 | T | ccRCC | 6.0 | no | 1100 | 183.3 |
RCC125 | T | ccRCC | 15.5, 8.1 | n.d. | 400 | 25.8 |
RCC116 | T | ccRCC | 15.8 | yes | 2380 | 150.6 |
RCC115 | T | ccRCC | 26.0 | yes | 12900 | 496.2 |
RCC113 | T | ccRCC | 10.1 | n.d. | 200 | 19.8 |
RCC108 | T | pRCC | 30.0 | yes | 1500 | 50.0 |
RCC103 | T | chRCC | 10.0 | yes | 4400 | 440.0 |
RCC101 | T | ccRCC | 7.5 | yes | 800 | 106.7 |
RCC98 | T | ccRCC | 21.1 | n.d. | 2100 | 99.5 |
RCC90 | T | ccRCC | 20.0 | n.d. | 10200 | 510.0 |
RCC75 | T | pRCC | 16.0 | n.d. | 2200 | 137.5 |
RCC73 | T | ccRCC | 10.0 | n.d. | 1300 | 130.0 |
RCC68 | T | ccRCC | 20.0 | yes | 2500 | 125.0 |
RCC395 | M (lymph node) | ccRCC | 1.4 | n.d. | 50 | 35.7 |
RCC333 | M (pancreas) | ccRCC | 10.9 | yes | 3000 | 275.2 |
RCC328 | M (contralateral k.) | ccRCC | 1.5 | n.d. | 300 | 200.0 |
RCC112 | M (adrenal gland) | ccRCC | 2.5 | n.d. | 700 | 280.0 |
RCC126 | NK | ccRCC | 8.9 | yes | 200 | 22.5 |