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Table 2 Univariate and multivariate analysis of intravesical tumor recurrence

From: Clinical significance of subepithelial growth patterns in non-muscle invasive bladder cancer

Variables

Cases (n)

Tumor recurrence

   

Univariate

Multivariate

   

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

T stage

      
 

a

104

1

-

  
 

1

26

1.40 (0.68-3.21)

0.32

  

Tumor grade (2004 WHO)

   

0.14

  
 

PUNLMP

13

1

-

  
 

LG

84

1.41 (0.50-4.00)

0.57

  
 

HG

33

2.17 (0.70-5.56)

0.2

  

Concomitant CIS

      
 

absent

123

1

-

  
 

present

7

1.32 (0.36-5.28)

0.20

  

Lymphovascular involvement

      
 

absent

110

1

-

  
 

present

20

1.75 (0.86-4.93)

0.11

  

Endophytic growth pattern

      
 

absent

90

1

-

  
 

present

40

0.76 (0.39-1.52)

0.45

  

von Brunn's nest involvement

      
 

absent

125

1

-

  
 

present

5

1.54 (0.29-9.94)

0.54

  

Multiplicity

      
 

solitary

70

1

-

1

-

 

multiple

60

1.91 (1.04-3.59)

0.038

1.93 (0.98-3.79)

0.058

Tumor diameter (cm)

      
 

< 3

99

1

-

1

-

 

≥ 3

31

2.04 (1.13-5.06)

0.023

2.10 (1.04-4.27)

0.040

Intravesical therapy

      
 

None

55

1

-

1

-

 

BCG

67

0.53 (0.23-0.96)

0.039

0.35 (0.18-0.71)

0.004

 

Anthracyclines

8

0.96 (0.28-3.21)

0.94

0.63 (0.24-2.38)

0.63