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Table 2 Univariate and multivariate analysis of intravesical tumor recurrence

From: Clinical significance of subepithelial growth patterns in non-muscle invasive bladder cancer

Variables Cases (n) Tumor recurrence
    Univariate Multivariate
    Hazard ratio (95% CI) p value Hazard ratio (95% CI) p value
T stage       
  a 104 1 -   
  1 26 1.40 (0.68-3.21) 0.32   
Tumor grade (2004 WHO)     0.14   
  PUNLMP 13 1 -   
  LG 84 1.41 (0.50-4.00) 0.57   
  HG 33 2.17 (0.70-5.56) 0.2   
Concomitant CIS       
  absent 123 1 -   
  present 7 1.32 (0.36-5.28) 0.20   
Lymphovascular involvement       
  absent 110 1 -   
  present 20 1.75 (0.86-4.93) 0.11   
Endophytic growth pattern       
  absent 90 1 -   
  present 40 0.76 (0.39-1.52) 0.45   
von Brunn's nest involvement       
  absent 125 1 -   
  present 5 1.54 (0.29-9.94) 0.54   
Multiplicity       
  solitary 70 1 - 1 -
  multiple 60 1.91 (1.04-3.59) 0.038 1.93 (0.98-3.79) 0.058
Tumor diameter (cm)       
  < 3 99 1 - 1 -
  ≥ 3 31 2.04 (1.13-5.06) 0.023 2.10 (1.04-4.27) 0.040
Intravesical therapy       
  None 55 1 - 1 -
  BCG 67 0.53 (0.23-0.96) 0.039 0.35 (0.18-0.71) 0.004
  Anthracyclines 8 0.96 (0.28-3.21) 0.94 0.63 (0.24-2.38) 0.63