Skip to main content

Table 3 Univariate and multivariate analysis for disease progression

From: Clinical significance of subepithelial growth patterns in non-muscle invasive bladder cancer

Variables Cases (n) Disease progression
    Univariate Multivariate
    Hazard ratio (95% CI) p value Hazard ratio (95% CI) p value
T stage       
  a 104 1 - 1 -
  1 26 20.69 (7.82-446.23) < 0.0001 20.94 (2.44-179.45) 0.006
Tumor grade (2004 WHO)       
  PUNLMP/LG 97 1 - 1 -
  HG 33 14.37 (3.25-126.40) 0.0013 2.97 (0.098-90.16) 0.53
Concomitant CIS       
  absent 123 1 -   
  present 7 ND 0.51   
Lymphovascular involvement       
  absent 110 1 - 1 -
  present 20 12.07 (7.49-733.68) 0.0002 1.23 (0.13-11.28) 0.86
Multiplicity       
  solitary 70 1 -   
  multiple 60 5.44 (0.84-20.60) 0.082   
Tumor diameter (cm)       
  < 3 99 1 - 1 -
  ≥ 3 31 16.93 (4.63-209.78) 0.0004 6.77 (0.69-66.8) 0.10
Endophytic growth pattern       
  absent 90 1 -   
  present 40 ND 0.096   
von Brunn's nest involvement       
  absent 125 1 -   
  present 5 5.82 (0.74-5617.98) 0.068   
Intravesical therapy       
  None 55 1 -   
  BCG 75 1.09 (0.20-5.99) 0.92