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Table 4 Relative expression of miR-21 and RECK in the malignant prostatic tissue in three profiles

From: miR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer

 

↓miR-21 and

↓RECK

↑miR-21 and

↓RECK

↓miR-21 and

↑RECK

P value

Gleason Score

    

< 7

56.0%

33.3%

31.3%

0.215

≥ 7

44.0%

67.7%

68.7%

 

Pathological Stage

    

pT2

52.0%

8.3%

53.3%

0.025

pT3

48.0%

91.7%

46.7%

 

PSA value

    

<10

60.0%

50.0%

37.5%

0.371

≥10

40.0%

50.0%

62.5%

 

Biochemical Recurrence

    

No

75.0%

36.4%

50.0%

0.087

Yes

25.0%

63.6%

50.0%

 
  1. miR-21 and RECK underexpressed, miR-21 overexpressed and RECK underexpressed, and miR-21 underexpressed and RECK overexpressed, correlated either with Gleason score, pathological stage, PSA serum value or biochemical recurrence. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 2-ΔΔCT).