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Table 4 Relative expression of miR-21 and RECK in the malignant prostatic tissue in three profiles

From: miR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer

  ↓miR-21 and
↓RECK
↑miR-21 and
↓RECK
↓miR-21 and
↑RECK
P value
Gleason Score     
< 7 56.0% 33.3% 31.3% 0.215
≥ 7 44.0% 67.7% 68.7%  
Pathological Stage     
pT2 52.0% 8.3% 53.3% 0.025
pT3 48.0% 91.7% 46.7%  
PSA value     
<10 60.0% 50.0% 37.5% 0.371
≥10 40.0% 50.0% 62.5%  
Biochemical Recurrence     
No 75.0% 36.4% 50.0% 0.087
Yes 25.0% 63.6% 50.0%  
  1. miR-21 and RECK underexpressed, miR-21 overexpressed and RECK underexpressed, and miR-21 underexpressed and RECK overexpressed, correlated either with Gleason score, pathological stage, PSA serum value or biochemical recurrence. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 2-ΔΔCT).