Figure 2
From: Valproic acid decreases urothelial cancer cell proliferation and induces thrombospondin-1 expression
Relative cell numbers by alamar blue assay for bladder cancer cell lines treated for three days with HDAC inhibitors at the indicated concentrations. Statistically significant differences (t-test, p < 0.05) from control are indicated by *. There were statistically significant reductions in cell number for all treatment conditions relative to untreated controls for UMUC3 cells. Similarly, all treatments except the 1 mM valproate condition showed significant reduction in T24 cell number.