Table 2 Prognostic factors for overall survival by univariate and multivariate Cox regression analysis
Univariate | Multivariate | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
parameter | category | n | Hazard ratio | 95%CI | p value | Hazard ratio | 95%CI | p value | ||
Treatment | D | 28 | 1.000 | 0.853 | ||||||
DE | 33 | 0.934 | 0.454 | 1.923 | ||||||
Age (years) | ≦70 | 30 | 1.000 | 0.549 | ||||||
> 70 | 31 | 0.808 | 0.401 | 1.628 | ||||||
Gleason Score | ≦7 | 17 | 1.000 | 0.259 | ||||||
> 8 | 39 | 1.558 | 0.718 | 3.381 | ||||||
PSA at PCa diagnosis (ng/ml) | ≦113 | 31 | 1.000 | 0.940 | ||||||
> 113 | 30 | 1.027 | 0.520 | 2.025 | ||||||
PSA at baseline (ng/ml) | ≦12.8 | 31 | 1.000 | < 0.001 | 1.000 | 0.017 | ||||
> 12.8 | 30 | 4.903 | 2.181 | 11.024 | 3.605 | 1.262 | 10.296 | |||
ECOG performance status | ≦1 | 53 | 1.000 | < 0.001 | 1.000 | 0.218 | ||||
2 | 8 | 5.567 | 2.366 | 13.098 | 1.803 | 0.706 | 4.605 | |||
Time from diagnosis to this chemothrapy (months) | ≦35 | 31 | 1.000 | 0.003 | 1.000 | 0.015 | ||||
> 35 | 30 | 0.351 | 0.172 | 0.715 | 0.286 | 0.104 | 0.782 | |||
Bone metastasis | no | 28 | 1.000 | 0.014 | 1.000 | 0.419 | ||||
yes | 33 | 2.383 | 1.165 | 4.873 | 0.646 | 0.224 | 1.862 | |||
No. of Docetaxel cycles | < 5 | 28 | 1.000 | < 0.001 | 1.000 | < 0.001 | ||||
<5 | 33 | 0.213 | 0.100 | 0.452 | 0.209 | 0.093 | 0.472 | |||
Hemoglobin (g/dl) | ≦12.0 | 33 | 1.000 | 0.120 | ||||||
> 12.0 | 28 | 0.580 | 0.289 | 1.163 | ||||||