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Table 4 Correlation between PGI-I and other BPH Measures (change from baseline) in all patients

From: Construct validation of patient global impression of severity (PGI-S) and improvement (PGI-I) questionnaires in the treatment of men with lower urinary tract symptoms secondary to benign prostatic hyperplasia

PGI-I (last visit)

n (%)

Mean IPSS change (SD)

Mean IPSS-QoL change (SD)

Mean BII change (SD)

Mean Qmax change (SD)

Very Much Better

99 (6.1%)

−14.4 (5.9)

−2.6 (1.6)

−5.2 (3.1)

3.7 (4.9)

Much Better

443 (27.2%)

−10.9 (5.6)

−2.0 (1.3)

−4.0 (2.9)

4.0 (5.6)

A Little Better

632 (38.8%)

−7.0 (5.4)

−1.0 (1.2)

−2.3 (2.7)

3.0 (5.0)

No Change

357 (21.9%)

−3.3 (5.2)

−0.3 (1.1)

−0.9 (2.7)

2.1 (4.3)

A Little Worse

65 (4.0%)

−0.2 (5.7)

0.0 (1.2)

−0.1 (3.0)

2.0 (4.8)

Much Worse

26 (1.6%)

3.5 (5.4)

0.5 (1.1)

1.8 (2.6)

1.3 (3.1)

Very Much Worse

6 (0.4%)

6.8 (5.1)

1.0 (0.9)

4.5 (2.1)

0.1 (2.0)

Overall comparison p-value

 

<0.001

<0.001

<0.001

<0.001

Pairwise comparison p-value

     

  Better vs. No change

 

<0.001

<0.001

<0.001

<0.001

  Better vs. Worse

 

<0.001

<0.001

<0.001

0.002

  No change vs. Worse

 

<0.001

<0.001

<0.001

0.534

Spearman’s Correlation

 

0.56**

0.53**

0.47**

−0.15**

  1. PGI-I: Patient Global Impression of Improvement; IPSS: International Prostate Symptom Scores; IPSS QoL: IPSS-Quality of Life (QoL), BII - Benign Prostatic Hyperplasia Impact Index; Qmax: peak urine flow rate; n: number of patients; SD: Standard Deviation. Overall and pairwise comparison p-values are from analysis of variance without adjusting for covariates. **: p<0.001.