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Table 2 Comparison of neoadjuvant hormonal therapy period treated with laparoscopic radical prostatectomy patients

From: Neoadjuvant hormonal therapy is a feasible option in laparoscopic radical prostatectomy

Variables

Group A*

Group B**

No. of patients

47

25

Mean age ± SD

67.4 ± 5.6

68.3 ± 4.7

Preoperative serum PSA ± SD, ng/mL

10.0 ± 3.9

9.38 ± 4.4

Biopsy Gleason grade, n(%)

 ≤ 3 + 3

20 (42.6)

10 (40.0)

 3 + 4, 4 + 3

20 (42.6)

5 (20.0)

 ≥ 4 + 4

7 (14.9)

10 (40.0)

D’Amico risk classification, n(%)

 low

11 (23.4)

3 (12.0)

 intermediate

17 (36.2)

7 (28.0)

 high

19 (40.4)

15 (60.0)

Kind of neoadjuvant hormonal therapy

 CAB

32 (68.1)

18 (72.0)

 anti-androgen alone

15 (31.9)

7 (28.0)

Pathological stage, n(%)

 pT2

42 (89.4)

20 (80.0)

 pT3a

3 (6.40)

4 (16.0)

 pT3b

2 (4.30)

1 (4.00)

Median operative time, min

286 (151–454)

270 (152–410)

Median blood loss, ml

600 (90–3928)

552 (95–1600)

Positive surgical margin, n(%)

13 (27.7)

7 (28.0)

Biochemical recurrence, n(%)

13 (27.7)

*1 (4.00)

  1. Patient characteristics and outcomes in two NHT patient groups (Group A: NHT on LRP for less than 3 months, Group B: NHT on LRP for more than 3 months) *p < 0.05.
  2. Group A*: laparoscopic radical prostatectomy cases treated with neoadjuvant hormonal therapy for less than 3 months.
  3. Group B**: laparoscopic radical prostatectomy cases treated with neoadjuvant hormonal therapy for more than 3 months.
  4. CAB: combined androgen blockade with anti-androgen and LHRH analogue. *p < 0.05.
  5. CAB: combined androgen blockade with anti-androgen and LHRH analogue.