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Table 3 Global H4K20 methylation levels are correlated to adverse clinical-pathological parameters

From: Alterations of global histone H4K20 methylation during prostate carcinogenesis

  H4K20me1 H4K20me2 H4K20me3
preoperative PSA† p = 0.122 p = 0.573 p = 0.151
pT-stage p = 0.122 p = 0.573 p = 0.157
capsular penetration p = 0.094 p = 0.469 p = 0.902
seminal vesicle infiltration p = 0.127 p = 0.947 p = 0.468
lymph node metastases p = 0.002 p = 0.196 p = 0.091
Gleason Score‡ p = 0.191 p = 0.021 p = 0.074
  1. † categorized: PSA < 4 ng/ml, 4-10 ng/ml, > 10 ng/ml; ‡ categorized: Gleason Sum ≤ 6, 7, ≥ 8