Figure 4From: Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model Combined treatment with radiation and diclofenac increased an induction of apoptosis compared with either alone. Cells were incubated for 24 hours, and treated with diclofenac (IC25) for 48 hours, then exposed to radiation (0, 2 Gy). Apoptosis induction was quantified using Cell Death Detection ELISA kit.Back to article page