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Table 3 Relative risks of death from disease and overall death within 5 years according to clinicopathological factors and RBM3 expression in all patients (n=343)

From: Decreased expression of RNA-binding motif protein 3 correlates with tumour progression and poor prognosis in urothelial bladder cancer

  

Risk of death from disease

 

Risk of death within 5 years

  

Univariable

Multivariable

 

Univariable

Multivariable

 

n (events)

HR (95% CI)

HR (95% CI)

n (events)

HR (95% CI)

HR (95% CI)

Age

      

Continuous

299 (100)

1.05 (1.03-1.07)

1.04 (1.02-1.07)

343 (123)

1.07 (1.05-1.08)

1.07 (1.05-1.08)

Gender

      

Female

72 (28)

1.00

1.00

83 (56)

1.00

1.00

Male

227 (72)

0.79 (0.51-1.23)

1.07 (0.68-1.67)

260 (167)

0.95 (0.70-1.29)

1.24 (0.91-1.70)

Stage

      

Ta

104 (13)

1.00

1.00

115 (61)

1,00

1.00

T1

97 (25)

2.20 (1.13-4.31)

1.87 (0.85-4.08)

116 (71)

1.37 (0.97-1.94)

1.44 (0.96-2.15)

T2-4

99 (62)

8.86 (4.86-16.16)

6.77 (3.21-14.26)

112 (91)

2.79 (2.01-3.87)

2.90 (1.92-4.40)

Grade

      

Low

75 (7)

1.00

1.00

82 (41)

1.00

1.00

High

224 (93)

5.75 (2.66-12.40)

1.52 (1.58-3.96)

261 (182)

2.04 (1.45-2.87)

0.90 (0.58-1.39)

RBM3 expression

      

Positive

232 (66)

1.00

1.00

266 (160)

1.00

1.00

Negative

67 (34)

2.55 (1.68-3.86)

1.65 (1.07-2.53)

77 (63)

2.10 (1.56-2.82)

1.54 (1.13—2.10)