Changes of neuregulin-1(NRG-1) expression in a rat model of overactive bladder induced by partial urethral obstruction: is NRG-1 a new biomarker of overactive bladder?

Table 2 Results of cystometric analysis of the experimental animals

	Control	OAB	OAB + 5-
			HMT
Micturition Interval	64.73 ± 4.68	27.97 ± 4.19^※	39.25 ± 6.02^※※
(Sec) (Mean ± SD)	64.73 ± 4.68	27.97 ± 4.19^※	39.25 ± 6.02^※※
Pressure Difference between Maximal Micturition Pressure and Basal Pressure (cmH2O) (Mean ± SD)	55.35 ± 4.55	50.79 ± 8.40	48.17 ± 4.99
Micturition Volume	0.612 ± 0.610	0.186 ± 0.049^※	0.270 ± 0.655^※※
(ml) (Mean ± SD)	0.612 ± 0.610	0.186 ± 0.049^※	0.270 ± 0.655^※※
Micturition Time	10.63 ± 0.83	11.73 ± 1.20^※	10.78 ± 1.49
(Sec) (Mean ± SD)	10.63 ± 0.83	11.73 ± 1.20^※	10.78 ± 1.49
Pressure Difference between Threshold Pressure and Basal Pressure	13.93 ± 1.05	9.47 ± 6.97	4.74 ± 3.74
(cmH2O) (Mean ± SD)	13.93 ± 1.05	9.47 ± 6.97	4.74 ± 3.74

OAB overactive bladder group; OAB + 5-HMT overactive bladder treated with 5-hydroxymethyl tolterodine group.
^※ Significant difference (P < 0.05) compared with the control group.
^※※ Significant difference (P < 0.05) compared with OAB group.

ISSN: 1471-2490