Characteristic | PSA†(n = 462) | Family PCa†(n = 458) | Family Ca†(n = 451) | Age of PCa presentation¥(n = 265) | Gleason score¥(n = 180) | Grade¥(n = 147) | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Marker (risk allele) | OR (95% CI)‡* | P§ | Q¶ | OR (95% CI)‡ | P§ | Q¶ | OR (95% CI)‡ | P§ | Q¶ | OR (95% CI)‡ | P§ | Q¶ | OR (95% CI)‡ | P§ | Q¶ | OR (95% CI)‡ | P§ | Q¶ |
rs6983561 (C) | 1.35 (1.04-1.74) | 0.02 | 0.40 | 1.40 (0.86-2.27) | 0.18 | 0.60 | 0.91 (0.51-1.62) | 0.75 | 0.84 | 0.81 (0.57-1.15) | 0.24 | 0.68 | 1.11 (0.72-1.71) | 0.63 | 0.81 | 1.73 (1.03-2.92) | 0.04 | 0.35 |
rs1859962 (G) | 1.28 (0.96-1.71) | 0.09 | 0.60 | 1.00 (0.61-1.65) | 0.99 | 0.99 | 0.58 (0.29-1.16) | 0.12 | 0.60 | 0.95 (0.64-1.42) | 0.82 | 0.86 | 1.22 (0.76-1.95) | 0.42 | 0.76 | 1.84 (1.05-3.22) | 0.03 | 0.35 |
rs13254738 (C) | 1.15 (0.87-1.52) | 0.33 | 0.60 | 1.04 (0.61-1.79) | 0.88 | 0.93 | 1.12 (0.67-1.89) | 0.66 | 0.79 | 1.06 (0.73-1.54) | 0.75 | 0.86 | 0.72 (0.46-1.13) | 0.15 | 0.68 | 1.16 (0.67-1.99) | 0.60 | 0.81 |
rs10090154 (T) | 0.89 (0.64-1.24) | 0.50 | 0.75 | 0.70 (0.34-1.43) | 0.33 | 0.60 | 1.44 (0.74-2.79) | 0.29 | 0.60 | 1.03 (0.64-1.65) | 0.91 | 0.91 | 0.79 (0.43-1.44) | 0.43 | 0.76 | 1.28 (0.66-2.47) | 0.47 | 0.76 |
rs4242382 (A) | 0.81 (0.61-1.09) | 0.17 | 0.60 | 0.87 (0.50-1.50) | 0.62 | 0.79 | 1.20 (0.66-2.18) | 0.54 | 0.75 | 1.06 (0.72-1.57) | 0.78 | 0.86 | 1.21 (0.74-1.96) | 0.45 | 0.76 | 1.46 (0.83-2.56) | 0.19 | 0.68 |
rs1465618 (A) | 1.29 (0.80-2.08) | 0.29 | 0.60 | 1.46 (0.68-3.16) | 0.33 | 0.60 | 1.43 (0.58-3.47) | 0.44 | 0.71 | 0.71 (0.39-1.29) | 0.26 | 0.68 | 1.54 (0.80-2.95) | 0.20 | 0.68 | 1.30 (0.56-3.01) | 0.54 | 0.81 |