Table 2 The results of the univariate analyses using three-sided stratifications
From: A combined index to classify prognostic comorbidity in candidates for radical prostatectomy
Category | Events | Hazard ratio | 95% CI | p* | 10-year survival | 95% CI |
|---|---|---|---|---|---|---|
PSA < 10 ng/mL | 138/1165 | 1 | 87.3% | 84.7-89.4% | ||
PSA 10–19.9 ng/mL | 58/398 | 1.03 | 0.76-1.41 | 0.8429 | 86.0% | 81.4-89.5% |
PSA 20+ ng/mL or neoadjuvant therapy | 105/598 | 1.26 | 0.97-1.64 | 0.0852 | 81.9% | 77.9-85.2% |
Gleason score <7 | 117/989 | 1 | 88.8% | 86.3-90.9% | ||
Gleason score 7 | 81/721 | 1.09 | 0.82-1.45 | 0.5600 | 87.7% | 84.1-90.5% |
Gleason score 8-10 | 103/421 | 3.19 | 2.35-4.34 | <0.0001 | 72.5% | 66.7-77.4% |
organ confined, pN0 | 162/1380 | 1 | 88.3% | 86.1-90.2% | ||
non confined, pN0 | 86/558 | 1.30 | 0.99-1.70 | 0.0637 | 84.4% | 80.4-87.7% |
pN1 | 53/193 | 3.14 | 2.09-4.72 | <0.0001 | 67.9% | 59.2-75.1% |
ASA 1 | 17/212 | 1 | 92.9% | 88.0-95.9% | ||
ASA 2 | 201/1561 | 1.83 | 1.27-2.65 | 0.0013 | 87.1% | 84.9-89.0% |
ASA 3 | 83/357 | 3.28 | 2.18-4.91 | <0.0001 | 73.3% | 67.2-78.4% |
Charlson score 0 | 146/1323 | 1 | 89.4% | 87.3-91.2% | ||
Charlson score 1 | 74/486 | 1.53 | 1.13-2.08 | 0.0057 | 82.8% | 78.0-86.6% |
Charlson score 2+ | 81/322 | 3.61 | 2.56-5.09 | <0.0001 | 73.0% | 66.7-78.3% |
NYHA 0 | 245/1877 | 1 | 86.4% | 84.4-88.2% | ||
NYHA 1 | 25/125 | 1.84 | 1.11-3.06 | 0.0181 | 77.0% | 67.0-84.4% |
NYHA 2+ | 31/129 | 2.01 | 1.26-3.22 | 0.0034 | 79.2% | 70.4-85.7% |
CCS 0 | 228/1804 | 1 | 87.2% | 85.2-89.0% | ||
CCS 1 | 40/211 | 1.65 | 1.12-2.45 | 0.0123 | 79.5% | 71.9-85.2% |
CCS 2+ | 33/116 | 3.11 | 1.87-5.16 | <0.0001 | 71.2% | 60.7-79.4% |
Disease count 0 | 64/619 | 1 | 91.2% | 88.2-93.4% | ||
Disease count 1 | 81/677 | 1.25 | 0.90-1.73 | 0.1822 | 87.2% | 83.6-90.0% |
Disease count 2+ | 156/835 | 2.00 | 1.53-2.61 | <0.0001 | 79.7% | 76.2-82.8% |
No diabetes | 249/1877 | 1 | 86.7% | 84.7-88.4% | ||
Diabetes without end organ damage | 27/157 | 1.47 | 0.93-2.32 | 0.0990 | 80.0% | 70.5-86.6% |
Diabetes with end organ damage | 25/97 | 3.35 | 1.86-6.04 | 0.0001 | 68.3% | 55.2-78.3% |
Body mass index <30 kg/m2 | 237/1775 | 1 | 86.4% | 84.4-88.3% | ||
Body mass index 30–34.9 kg/m2 | 56/327 | 1.55 | 1.11-2.16 | 0.0094 | 81.4% | 75.8-85.8% |
Body mass index 35+ kg/m2 | 8/29 | 6.90 | 2.10-22.68 | 0.0015 | 69.8% | 46.1-84.7% |