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Table 3 Hazards ratio estimate and confidence intervals from proportional hazards modeling of overall survival

From: Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer

  

Univariate analysis

Multivariate analysis

Hazard ratio

95% C.I.

P value

Hazard ratio

95% C.I.

P value

Age

 

0.987

0.962-1.013

0.324

0.994

0.967-1.021

0.647

Nadir PSA level

<0.2

1

  

1

  
 

0.2-4

3.038

1.852-4.982

<0.001

2.329

1.342-4.040

0.003

 

≥4

7

4.109-11.925

<0.001

5.221

2.757-9.889

<0.001

Time from PADT to nadir

≥12

1

  

1

  
 

6-12

2.544

1.473-4.393

0.001

1.483

0.789-2.789

0.221

 

<6

6.918

4.174-11.467

<0.001

4.008

2.137-7.517

<0.001

Time from PADT to CRPC

No CRPC

1

  

1

  
 

≥12

0.963

0.509-1.822

0.907

0.718

0.367-1.407

0.335

 

6-12

4.323

2.310-8.089

<0.001

1.419

0.664-3.031

0.367

 

<6

9.021

4.570-17.808

<0.001

1.712

0.731-4.005

0.215

  1. 95% CI.: 95% confidence interval.
  2. PADT: primary androgen deprivation therapy.
  3. CRPC: castration resistant prostate cancer.
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BMC Urology

ISSN: 1471-2490

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