Table 1 Biopsy and TRUS results
Biopsy results | Previously negative biopsy (%) | Active surveillance (%) | P-value |
|---|---|---|---|
% Positive | 27/78 (34.6%) | 42/49 (85.7%) | 0.0001 |
% Positive in AZ | 17/78 (21.8%) | 17/49 (34.7%) | 0.1492 |
% TZ involved | 8/78 (10.3%) | 5/49 (10.2%) | 1 |
% AZ only | 1/78 (1.3%) | 2/49 (4%) | 0.56 |
% AZ findings changed risk stratification | 3/78 (3.8%) | 3/49 (6.1%) | 0.68 |
% Only TZ | 0/78 (0%) | 0/49 (0%) | 1 |
% Cores involved | 4.5/26 (17.3%) | 3.1/26 (11.9%) | 0.0423 |
Clinically insignificant cancer* | 10/27 (37%) | 25/49 (51%) | 0.3366 |
Gleason ≥ 7 anywhere | 12/27 (44.4%) | 12/49 (24.5%) | 0.1215 |
Gleason ≥ 7 in AZ | 9/27 (33.3%) | 5/49 (10.2%) | 0.0273 |
TRUS results | |||
Hypoechoic lesion anywhere | 26/78 (33.3%) | 12/49 (24.5%) | 0.3248 |
Hypoechoic lesion in AZ | 8/78 (10.3%) | 0/49 (0%) | 0.0228 |
Hypoechoic lesion in AZ + Cancer in AZ | 5/78 (6.4%) | 0/49 (0%) | 0.1555 |