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Figure 3 | BMC Urology

Figure 3

From: Development of an in vitro model to measure bioactivity of botulinum neurotoxin A in rat bladder muscle strips

Figure 3

A-C: Measured inhibition of bladder strip contraction and fitted curves. Measured inhibition of bladder strip contraction after incubation in 0 nM (control), 0.2 nM and 0.3 nM BoNT-A in time (hours) with the fitted curves. Imax = calculated maximum of inhibition, b = shape parameter of the curve, t = time after highest peak forces of EFS at start of incubation (hours), m = mid inhibition time (hours), R2 = predictive accuracy of the fitted curve. A = run 1  = 0 nM (control),  = 0.3 nM BoNT-A. B = run 3  = 0 nM (control), O = 0.2 nM BoNT-A. C = run 4 O = 0.2 nM BoNT-A,  = 0.3 nM BoNT-A.

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