Table 1 The results of maximum inhibition of strip contraction calculated by a log-logistic model which represents diffusion
BoNT-A (nM) | run | Imax | CI | m | CI | b | CI | R2 |
|---|---|---|---|---|---|---|---|---|
0.3 | 1a | 0.42 | 0.37-0.47 | 2.33 | 2.22-2.44 | 6.44 | 5.33-7.54 | 0.99 |
0.3 | 2a | 0.62 | 0.46-0.77 | 1.49 | 1.18-1.80 | 3.35 | 1.90-4.79 | 0.99 |
0.3 | 4a | 1.00 | 0.66-1.33 | 1.80 | 1.31-2.28 | 3.23 | 1.55-4.90 | 0.99 |
0.2 | 3a | 0.99 | 0.61-1.37 | 2.08 | 1.33-2.82 | 2.44 | 1.54-3.33 | 0.99 |
0.2 | 4b | 0.82 | min 0.02- 1.65 | 2.43 | min 0.36-5.22 | 1.83 | 0.59-3.08 | 0.99 |
0.2 | 5a | 1.00 | min 0.25-2.25 | 3.26 | 0.51-6.01 | 2.96 | 0.89-5.03 | 0.98 |
0.03 | 5b | 0.06 | 0.05-0.08 | 1.19 | 0.87-1.50 | 4.45 | min 0.42-9.31 | 0.96 |
0.03 | 6a | 0.83 | min 8.04-9.71 | 7.51 | min 49.76-64.79 | 2.02 | min 1.25-5.30 | 0.89 |
0 | 1b | 0.02 | min 17.7-17.7 | 0.52 | min 3304-3305 | 0.32 | min 420-420 | • |
0 | 2b | 0.16 | 0.03-0.29 | 0.24 | min 1.38-1.87 | 1.83 | min 18.0-21.7 | 0.35 |
0 | 3b | 0.01 | min 19.4-19.4 | 2.70 | min 2067-2067 | 3.01 | min 978-985 | • |