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Table 4 Frequencies of the various complications according to type of treatment* among men aged between 50 and 69 with newly managed prostate cancer (PCa) in 2009 and still alive after two years, and comparison with two control groups without PCa, with or without surgical treatment for benign prostatic hyperplasia (BPH)

From: Prostate cancer outcomes in France: treatments, adverse effects and two-year mortality

  Prostatectomy External beam radiotherapy Hormone therapy Treated Untreated Control groups without PCA
PCa PCa***
  Alone With another treatment** Alone Alone All   Without BPH surgery With BPH surgery
N 9,035 2,159 941 882 15,623 3,107 43,099 1,026
Mean age (years) 61.8 61.8 63.6 62.4 62.1 62.5 57.8 60.5
Complications % % %   % % % %
Erectile dysfunction         
Two years 61.4 47.9° 7.2° 6.8° 45.8 9.6° 0.3° 1.5°
  Drug treatment 61.3 47.9 7.2 6.8 45.7 9.5 0.3 1.5
  Penile prosthesis 0.2 0.2 0.04 0.0 0.2 0.1 0.00 0.00
First year 53.2 38.1° 2.6° 4.7° 38.7 8.1° 0.2° 1.0°
  Drug treatment 53.1 38.1 2.6 4.7 38.6 8.0 0.2 1.0
  Penile prosthesis 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Second year 41.5 31.8° 6.3° 4.4° 30.8 6.4° 0.2° 1.1°
  Drug treatment 41.3 31.8 6.3 4.4 30.7 6.3 0.2 1.1
  Penile prosthesis 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0
Urinary disorders         
Two years 23.7 27.9° 14.4° 8.7° 21.6 12.3° 0.4° 5.6°
  Drug treatment 18.0 21.6 12.3 7.4 17.0 9.4 0.3 4.8
  External devices 7.7 9.3 2.4 1.8 6.3 3.8 0.1 0.8
  Surgical procedure 2.1 1.2 0.00 0.1 1.4 0.6 0.00 0.00
First year 20.1 22.8 10.9° 4.7° 17.5 10.4° 0.2° 3.7°
  Drug treatment 14.7 16.0 8.9 4.0 13.1 7.5 0.2 3.2
  External devices 7.2 8.9 2.2 1.1 5.8 3.3 0.1 0.5
  Surgical procedure 0.5 0.2 0.0 0.1 0.3 0.5 0.0 0.0
Second year 9.0 11.5° 7.6 6.0° 9.0 5.5° 0.2° 3.5°
  Drug treatment 7.2 10.3 5.7 4.8 7.6 4.2 0.2 3.0
  External devices 1.4 1.5 1.9 1.2 1.3 1.6 0.1 0.4
  Surgical procedure 1.7 1.0 0.0 0.1 1.1 0.2 0.0 0.0
Clot removal         
  Surgical procedure 1.2 1.2 1.0 1.3 1.2 1.2 0.00° 0.3°
Urethral stricture         
  Surgical procedure 1.6 1.9 1.5 1.1 1.4 2.2 0.0° 1.3
Bladder neck stenosis         
  Surgical procedure 2.0 2.2 0.3° 1.0° 1.9 1.7 0.00° 0.9°
Radiation-induced inflammation         
  Hospitalisation 0.0 1.1° 3.2° 0.1 0.7 0.3° 0.00° 0.00°
Acute urinary retention         
  Surgical procedure 1.4 1.3 12.2 9.9° 3.5 19.3° 0.00° 3.6
Urethral-rectal fistula         
  Hospitalisation 0.5 0.4 0.00 0.1° 0.3 0.0° 0.00° 0.00°
None 28.1 35.8° 69.3° 76.9° 40.1 63.5° 99.3° 89.0°
Drug treatment         
  Antidepressants 11.3 11.4 12.2 15.9 12.0 12.2 7.1° 11.7
  Anxiolytics 15.3 18.1 21.1° 19.8 17.1 15.0° 10.4° 16.5
  1. *Hospitalisation: primary diagnosis, surgical treatment: presence of a specific surgical procedure code, external devices and medication: reimbursement codes.
  2. **Patients without treatment during the two years but with a primary diagnosis of PCa during hospitalisation or long-term chronic disease status for PCa.
  3. ***External beam radiotherapy and/or hormone therapy.
  4. Frequencies are age-standardised for men aged between 50 and 69 covered by the general scheme.
  5. °p < 0.05 for comparisons of frequencies between prostatectomy alone and prostatectomy combined with another treatment, external beam radiotherapy, for comparisons between untreated PCa and treated PCa, for comparisons between treated PCa and each control group.