Table 4 Frequencies of the various complications according to type of treatment* among men aged between 50 and 69 with newly managed prostate cancer (PCa) in 2009 and still alive after two years, and comparison with two control groups without PCa, with or without surgical treatment for benign prostatic hyperplasia (BPH)
From: Prostate cancer outcomes in France: treatments, adverse effects and two-year mortality
Prostatectomy | External beam radiotherapy | Hormone therapy | Treated | Untreated | Control groups without PCA | |||
|---|---|---|---|---|---|---|---|---|
PCa | PCa*** | |||||||
Alone | With another treatment** | Alone | Alone | All | Without BPH surgery | With BPH surgery | ||
N | 9,035 | 2,159 | 941 | 882 | 15,623 | 3,107 | 43,099 | 1,026 |
Mean age (years) | 61.8 | 61.8 | 63.6 | 62.4 | 62.1 | 62.5 | 57.8 | 60.5 |
Complications | % | % | % | % | % | % | % | |
Erectile dysfunction | ||||||||
Two years | 61.4 | 47.9° | 7.2° | 6.8° | 45.8 | 9.6° | 0.3° | 1.5° |
Drug treatment | 61.3 | 47.9 | 7.2 | 6.8 | 45.7 | 9.5 | 0.3 | 1.5 |
Penile prosthesis | 0.2 | 0.2 | 0.04 | 0.0 | 0.2 | 0.1 | 0.00 | 0.00 |
First year | 53.2 | 38.1° | 2.6° | 4.7° | 38.7 | 8.1° | 0.2° | 1.0° |
Drug treatment | 53.1 | 38.1 | 2.6 | 4.7 | 38.6 | 8.0 | 0.2 | 1.0 |
Penile prosthesis | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
Second year | 41.5 | 31.8° | 6.3° | 4.4° | 30.8 | 6.4° | 0.2° | 1.1° |
Drug treatment | 41.3 | 31.8 | 6.3 | 4.4 | 30.7 | 6.3 | 0.2 | 1.1 |
Penile prosthesis | 0.2 | 0.2 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 |
Urinary disorders | ||||||||
Two years | 23.7 | 27.9° | 14.4° | 8.7° | 21.6 | 12.3° | 0.4° | 5.6° |
Drug treatment | 18.0 | 21.6 | 12.3 | 7.4 | 17.0 | 9.4 | 0.3 | 4.8 |
External devices | 7.7 | 9.3 | 2.4 | 1.8 | 6.3 | 3.8 | 0.1 | 0.8 |
Surgical procedure | 2.1 | 1.2 | 0.00 | 0.1 | 1.4 | 0.6 | 0.00 | 0.00 |
First year | 20.1 | 22.8 | 10.9° | 4.7° | 17.5 | 10.4° | 0.2° | 3.7° |
Drug treatment | 14.7 | 16.0 | 8.9 | 4.0 | 13.1 | 7.5 | 0.2 | 3.2 |
External devices | 7.2 | 8.9 | 2.2 | 1.1 | 5.8 | 3.3 | 0.1 | 0.5 |
Surgical procedure | 0.5 | 0.2 | 0.0 | 0.1 | 0.3 | 0.5 | 0.0 | 0.0 |
Second year | 9.0 | 11.5° | 7.6 | 6.0° | 9.0 | 5.5° | 0.2° | 3.5° |
Drug treatment | 7.2 | 10.3 | 5.7 | 4.8 | 7.6 | 4.2 | 0.2 | 3.0 |
External devices | 1.4 | 1.5 | 1.9 | 1.2 | 1.3 | 1.6 | 0.1 | 0.4 |
Surgical procedure | 1.7 | 1.0 | 0.0 | 0.1 | 1.1 | 0.2 | 0.0 | 0.0 |
Clot removal | ||||||||
Surgical procedure | 1.2 | 1.2 | 1.0 | 1.3 | 1.2 | 1.2 | 0.00° | 0.3° |
Urethral stricture | ||||||||
Surgical procedure | 1.6 | 1.9 | 1.5 | 1.1 | 1.4 | 2.2 | 0.0° | 1.3 |
Bladder neck stenosis | ||||||||
Surgical procedure | 2.0 | 2.2 | 0.3° | 1.0° | 1.9 | 1.7 | 0.00° | 0.9° |
Radiation-induced inflammation | ||||||||
Hospitalisation | 0.0 | 1.1° | 3.2° | 0.1 | 0.7 | 0.3° | 0.00° | 0.00° |
Acute urinary retention | ||||||||
Surgical procedure | 1.4 | 1.3 | 12.2 | 9.9° | 3.5 | 19.3° | 0.00° | 3.6 |
Urethral-rectal fistula | ||||||||
Hospitalisation | 0.5 | 0.4 | 0.00 | 0.1° | 0.3 | 0.0° | 0.00° | 0.00° |
None | 28.1 | 35.8° | 69.3° | 76.9° | 40.1 | 63.5° | 99.3° | 89.0° |
Drug treatment | ||||||||
Antidepressants | 11.3 | 11.4 | 12.2 | 15.9 | 12.0 | 12.2 | 7.1° | 11.7 |
Anxiolytics | 15.3 | 18.1 | 21.1° | 19.8 | 17.1 | 15.0° | 10.4° | 16.5 |