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Table 2 Sensitivity and specificity of ALA, DRE, PSA, %sPSA, PSAD and TRUS

From: Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid

  Sensitivity Specificity
ALA 74.1% 70.2%
DRE 44.4% 91.2%
PSAD (cut-off 0.15) 93.8% 29.8%
%fPSA (cut-off 20%) 78.7% 26.3%
PSA (cut-off 4ng/ml) 60.1% 50.0%
TRUS 34.6% 96.5%
  1. Abbreviation: ALA aminolevulinic acid, DRE digital rectal examination, TRUS transrectal ultrasinography, PSAD PSA density, %fPSA percent free PSA.