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Table 2 Univariate analysis of the impact of various clinicopathologic factors on the risk of biochemical recurrence after salvage ADT

From: Ultra-early versus early salvage androgen deprivation therapy for post-prostatectomy biochemical recurrence in pT2-4N0M0 prostate cancer

 

No. of patients

p-value

Treatment group

 

0.0279*

  Ultra-early salvage ADT

51

  Early salvage ADT

70

Age, years

 

0.0798

  <70

82

  ≥70

39

Preoperative PSA, ng/ml

 

0.0493*

  <20

107

  ≥20

14

Pathologic Gleason score

 

0.0043*

  ≤7

101

  ≥8

20

Pathologic tumor stage

 

0.5690

  ≤2

77

  ≥3

44

Extraprostatic extension

 

0.7106

  0

79

  1

42

Lymphovascular invasion

 

0.4606

  0

92

  1

29

Positive resection margin

 

0.4467

  0

41

  1

80

Seminal vesicle invasion

 

0.3978

  0

117

  1

4

Perineural invasion

 

0.5035

  0

43

  1

78

 
  1. ADT, androgen deprivation therapy; *statistically significant; PSA, prostate-specific antigen.