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Table 2 Comparison of other studies with information from PLESS

From: Finasteride in the treatment of clinical benign prostatic hyperplasia: A systematic review of randomised trials

A. Prostate volume (cm3)

  

PLESS

Other studies (without PLESS)

  

Finasteride

Placebo

Finasteride

Placebo

Baseline

Number

157

155

2719

2696

 

Value

55.0

54.0

43.1

44.2

24 months

Number

130

119

2146

2140

 

Value

45.1

58.3

31.5

41.5

Mean change from baseline at 24 mths

-9.9

4.3

-10.6

3.3

B. Maximum urinary flow rate (mL/s)

  

PLESS

Other studies (without PLESS)

  

Finasteride

Placebo

Finasteride

Placebo

Baseline

Number

1125

1127

2991

2923

 

Value

11.0

11.0

10.5

10.3

24 months

Number

786

720

1806

1803

 

Value

12.6

11.4

12.4

11.3

Mean change from baseline at 24 mths

1.6

0.4

1.9

1.0

  1. Number of patients at baseline, or remained in the studies at 24 months