Adverse effect | Number of studies | Time point (months) | Harmed with finasteride 5 mg | Harmed with placebo | Relative risk (95% CI) | NNT (95% CI) | ||
---|---|---|---|---|---|---|---|---|
 |  |  | Number | Percent | Number | Percent |  |  |
Serious adverse effects | 2 | 12 | 437/3557 | 12 | 150/1175 | 13 | 1.0 (0.8 to 1.1) | n/c |
Any sexual dysfunction | 1 | 12 | 239/1736 | 14 | 38/579 | 7 | 2.1 (1.5 to 2.9) | 14 (10 to 22) |
Decreased libido | 5 | 12 | 269/5688 | 5 | 86/3296 | 3 | 2.0 (1.6 to 2.5) | 47 (35 to 74) |
Impotence | 6 | 12 | 439/5394 | 8 | 117/3551 | 3 | 2.2 (1.8 to 2.7) | 24 (20 to 31) |
Ejaculation disorder | 5 | 12 | 137/5688 | 2 | 19/3296 | 0.6 | 3.6 (2.2 to 6.0) | 55 (43 to 74) |
Acute urinary retention | 3 | 12 | 17/3803 | 0.4 | 9/1430 | 0.6 | 0.8 (0.4 to 1.9) | n/c |
 | 1 | 24 | 24/1450 | 2 | 54/1452 | 4 | 0.5 (0.3 to 0.7) | 49 (31 to 112) |
 | 1 | 48 | 42/1542 | 3 | 99/1516 | 7 | 0.4 (0.3 to 0.6) | 26 (19 to 44) |
BPH related surgery | 5 | 12 | 54/4410 | 1 | 24/2035 | 1 | 1.1 (0.7 to 1.7) | n/c |
 | 2 | 24 | 85/1760 | 5 | 142/1755 | 8 | 0.6 (0.5 to 0.8) | 31 (21 to 61) |
 | 1 | 48 | 69/1542 | 4 | 152/1516 | 10 | 0.5 (0.3 to 0.6) | 18 14 to 27) |
Prostate cancer | 2 | 12 | 9/3557 | 0.3 | 5/1175 | 0.4 | 0.6 (0.2 to 0.8) | n/c |
 | 1 | 24 | 3/310 | 1 | 6/303 | 2 | 0.5 (0.1 to 1.9) | n/c |
 | 1 | 48 | 76/1524 | 0.5 | 76/1516 | 0.5 | 1.0 (0.7 to 1.4) | n/c |