Figure 1
From: Interstitial cystitis antiproliferative factor (APF) as a cell-cycle modulator
Representative DNA frequency distributions DNA frequency distributions from 10 μl mock treated (top panel) and 10 μl APF treated (bottom panel) normal bladder epithelial cell cultures show an APF associated increase in the proportion of cells with tetraploid DNA value. The presence of cells with octaploid DNA values suggests the cultures contain a mixture of cycling diploid and tetraploid cells.