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Table 1 Review of published cases of giant cell lesions of the kidney and renal pelvis

From: Primary de novo malignant giant cell tumor of kidney: a case report

Age

Sex

Location

Immunoreactivity

Associated Malignancy

Outcome

Author & Reference

Year

56

M

Renal Parenchyma

Vimentin+, CD68+, Cytokeratin-ve, CAM 5.2-ve, AE1/AE3-ve

Malignant fibrous histiocytoma (MFH)

Disease free at 1 year

Chen C.H et al. [22]

2003

55

F

Renal Parenchyma

CD68+

Associated sarcomatoid spindle cells with osteoid production (osteosarcoma)

Disease free at 6 months

Lee, C.H et al. [19]

2003

30

M

Renal Parenchyma

Keratin & EMA -ve, Focally vimentin+

Clear cell type RCC, sarcomatoid

Disease free at 14 months

Koga, F. et al [20]

2000

81

M

Renal Parenchyma

CD68++ Scattered cytokeratin+, S100+

No

Died 2 months later

Heller, K.N et al. [2]

1998

55

F

Renal Parenchyma

CD68+, CAM2.5+, AE1/3+, EMA+, Vimentin+ (Keratin positive)

No associated sarcomatoid component

Disease free at 9 months

Chetty R, Cvijan D [14]

1997

69

M

Renal pelvis

S100+, CD68+, EMA+; Vimentin+

Papillary TCC

Liver and lung metastasis in 5 months

Molinie, V. [17]

1997

75

F

Renal Parenchyma

CD68+

Clear cell type RCC and sarcomatoid

N/A

el-Naggar, A.K et al. [15]

1993

64

M

Renal pelvis

N/A

In-situ TCC

N/A

Borg-Grech, A. et al. [13]

1987

56

M

Renal pelvis

N/A

Papillary TCC

Disease free at one month

Kenney, R.M et al. [16]

1984

60

M

Renal pelvis

N/A

No

Disease free at 1 year

Kimura, K et al. [21]

1983

77

F

Renal pelvis

N/A

SCC of the renal pelvis

N/A

Hou, L.T & Willis, R.A [18]

1963

79

F

Renal Parenchyma

N/A

Tubular and papillary adenocarcinoma

N/A

Hou, L.T & Willis, R.A [18]

1963

  1. TCC = Transitional cell carcinoma SCC = Squamous call carcinoma M = Male F = Female