Table 3 Organ-specific stromal mesenchyme cell genes. Listed are the candidates identified through array analysis. Fold difference in the last column of each grouping provides a rough estimate of the level of differential expression between the two cell types.
From: Stromal mesenchyme cell genes of the human prostate and bladder
Prostate Stromal Genes | Bladder Stromal Genes | ||||
|---|---|---|---|---|---|
Gene Description | Gene | Fold | Gene Description | Gene | Fold |
proenkephalin | PENK | 26.41 | B-factor, properdin | BF | 44.23 |
stanniocalcin 1 | STC1 | 20.86 | argininosuccinate synthetase | ASS | 19.36 |
trophinin | TRO | 13.41 | methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase | MTHFD2 | 19.04 |
RAB27B, member RAS oncogene family | RAB27B | 12.27 | claudin 11 (oligodendrocyte transmembrane protein) | CLDN11 | 18.25 |
REV3-like, catalytic subunit of DNA polymerase z (yeast) | REV3L | 10.68 | interleukin 1, b | IL1B | 17.57 |
CD59 antigen p18-20 | CD59 | 10.19 | carbonic anhydrase XII | CA12 | 16.49 |
matrix metalloproteinase 3 (stromelysin 1, progelatinase) | MMP3 | 10.06 | pirin | PIR | 15.52 |
homolog of rat orphan transporter v7-3 | NTT73 | 9.12 | osteoblast specific factor 2 (fasciclin I-like) | OSF-2 | 14.59 |
ras-induced senescence 1 | RIS1 | 9.05 | asparagine synthetase | ASNS | 12.96 |
chondroitin b1,4 N-acetylgalactosaminyltransferase | ChGn | 6.9 | inositol(myo)-1(or 4)-monophosphatase 2 | IMPA2 | 9.85 |
bone morphogenetic protein 2 | BMP2 | 6.68 | aldehyde dehydrogenase 1 family, member A1 | ALDH1A1 | 9.48 |
sprouty homolog 4 (Drosophila) | SPRY4 | 6.29 | prostaglandin I2 (prostacyclin) synthase | PTGIS | 9.24 |
endothelin receptor type B | EDNRB | 5.46 | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-a (3-a)-hydroxysteroid dehydrogenase) | AKR1C1 | 9.2 |
interleukin 7 receptor | IL7R | 5.44 | BCL2 binding component 3 | BBC3 | 9.06 |
tenascin C (hexabrachion) | TNC | 5.29 | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | CXCL12 | 8.65 |
tissue factor pathway inhibitor 2 | TFPI2 | 5.13 | activin A receptor, type II | ACVR2 | 8.03 |
plasminogen activator | PLAT | 5.09 | hyaluronan synthase 3 | HAS3 | 7.34 |
transcription factor 21 | TCF21 | 4.76 | GDNF family receptor a1 | GFRA1 | 7.12 |
KIAA1373 protein | KIAA1373 | 4.42 | activating transcription factor 5 | ATF5 | 6.31 |
UDP-N-acetyl-a-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 | GALNT7 | 4.25 | protein tyrosine phosphatase, receptor type, D | PTPRD | 5.76 |
SEC14-like 2 protein (S. cerevisiae) | SEC14L2 | 3.54 | growth arrest-specific 1 | GAS1 | 5.49 |
gap junction protein, a7, 45kDa (connexin 45) | GJA7 | 3.21 | Ca2+-dependent activator protein for secretion | CADPS | 5.25 |
| Â | Â | Â | paired-like homeodomain transcription factor 2 | PITX2 | 4.86 |
| Â | Â | Â | tryptophanyl-tRNA synthetase | WARS | 4.76 |
| Â | Â | Â | phosphogluconate dehydrogenase | PGD | 4.56 |
| Â | Â | Â | CUG triplet repeat, RNA binding protein 2 | CUGBP2 | 4.46 |
| Â | Â | Â | GATA binding protein 6 | GATA6 | 4.4 |
| Â | Â | Â | collectin sub-family member 12 | COLEC12 | 3.94 |
| Â | Â | Â | stanniocalcin 2 | STC2 | 3.86 |