Table 5 TUNA vs. TURP: results of meta-analysis of variables of efficacy.
Variable | Studies (No. patients) | TUNA Difference in means (% improvement) | TURP Difference in means (% improvement) | TUNA vs. TURP Difference in means (95% CI), P value |
|---|---|---|---|---|
Symptom score | ||||
3 months | 350,53,56 (384) | -12.49 (57%) | -13.85 (64 %) | 1.33 (-.81,3.47), .22 |
1 year | 452–54,57 (427) | -12.09 (55%) | -15.48 (71%) | 3.69 (2.09, 5.29), .00 |
2 years | 352,54,57 (368) | -10.42 (48%) | -14.83 (68%) | 4.72 (3.77, 5.69), .00 |
3 years | 252,54 (273) | -9.83 (45%) | -14.63 (67%) | 4.82 (4.25, 5.39), .00 |
4 years | 154 (121) | -10.80 (50%) | -16.50 (76%) | 5.70 (4.67, 6.73), .00 |
5 years | 154 (121) | -13.30 (61%) | -13.30 (61%) | 0 (-0.99, 0.99), 1.0 |
Quality of life score | ||||
3 months | 350,53,56 (277) | -4.47 (54%) | -3.65 (47%) | -0.40 (-1.25, 0.45), .35 |
1 year | 352–54 (332) | -4.05 (49%) | -4.34 (56%) | 0.63 (0.12, 1.15), .01 |
2 years | 252,54 (273) | -3.90 (47%) | -5.67 (74%) | 1.69 (-1.05, 4.44), .22 |
3 years | 252,54 (273) | -4.17 (50%) | -5.18 (67%) | 1.02 (0.14, 1.90), .02 |
4 years | 154 (121) | -6.6 (80%) | -8.90 (116%) | 2.3 (1.84, 2.76), .00 |
5 years | 154 (121) | -8.0 (96%) | -8.60 (112%) | 0.6 (0.21, 0.99), .00 |
Qmax (mL/s) | ||||
3 months | 350,53,56 (277) | 4.85 (57%) | 11.37 (148%) | -6.48 (-7.29, -5.68), .00 |
1 year | 452–54,57 (375) | 6.49 (76%) | 12.23 (160%) | -5.9 (-7.73, -4.08), 00 |
2 years | 450,54,57,58 (430) | 4.55 (53%) | 12.17 (159%) | -7.93 (-11.1, -4.77), .00 |
3 years | 252,54 (273) | 5.6 (66%) | 10.80 (141%) | -5.32 (-6.78, -3.85), .00 |
4 years | 154 (121) | 2.9 (34%) | 10.10 (132%) | -7.2 (-7.99, -6.4), .00 |
5 years | 154 (121) | 2.6 (30%) | 9.8 (127%) | -7.2 (-7.93, -6.47), .00 |
PVR (ml) | ||||
3 months | 350,53,56 (277) | -27.76 (31%) | -44.66 (44%) | 23.82 (-19.35, 66.97), .28 |
1 year | 353,54,57 (223) | -21.92 (24%) | -52.42 (51%) | 24.97 (20.90, 29.05), .00 |
2 years | 354,57,58 (278) | -27.58 (31%) | -69.24 (68%) | 35.8 (25.00, 46.61), .00 |
5 years | 154 (121) | -31.40 (35%) | -54.50 (53%) | 23.1 (12.16, 43.04), .00 |
PdetQmax (cm of water) | ||||
6 months | 251,58 (235) | -20.52 (27%) | -32.4 (45%) | 13.12 (0.6, 25.65), .04 |
2 years | 158 (114) | -28.56 (38%) | -42 (58%) | 13.44 (11.6,15.27), .00 |
No. Abrams-Griffiths | ||||
6 months | 151 (121) | -24 (39%) | -47.40 (81%) | 23.4 (20.7, 26.2), .00 |
Prostatic size | ||||
3 months | 250,58 (235) | -2.66 (7%) | -12.98 (34%) | 10.13 (-7.02,27.3), .02 |
1 year | 150 (121) | -0.9 (2.4%) | -5.5 (17%) | 6.4 (4.8,7.96), .00 |
2 years | 253,58 (173) | -6.46 (15%) | -12.78 (34%) | 5.52 (-2.7,13.75), .19 |