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Figure 1 | BMC Urology

Figure 1

From: Substance P induces localization of MIF/α1-inhibitor-3 complexes to umbrella cells via paracellular transit through the urothelium in the rat bladder

Figure 1

Substance P-induced A1-I3 immunostaining in umbrella cells. A1-I3 immunostaining in bladders from intact (A; B) and saline treated rats (C) showed A1-I3 in the interstitial spaces and in the lamina propria immediately below the urothelium, but not in the urothelium. In substance P-treated animals (D), however, A1-I3 immunostaining was detected in the urothelium, particularly on umbrella cells. Note also immunostaining surrounding (but not intracellular) in the basal and intermediate layers of the urothelium (see insert) in SP-treated rats. Calibration bar: A = 400 um; B, C, D = 100 um; insert = 50 um.

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BMC Urology

ISSN: 1471-2490

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