Skip to main content
Figure 7 | BMC Urology

Figure 7

From: Substance P induces localization of MIF/α1-inhibitor-3 complexes to umbrella cells via paracellular transit through the urothelium in the rat bladder

Figure 7

Effect of Substance P-treatment on specific MIF/A1-I3 complexes. Substance P treatment decreased the total MIF detected in bladder homogenates (using WB under non-reducing conditions) and this decrease was statistically significant (A). In addition, examining the changes in individual bands (under non-reducing conditions) showed that substance P treatment caused a significant decrease in the 170-kDa band in bladder homogenates, while changes in other bands did not reach statistical significance (B). SP treatment also increased the total amount of A1-I3 in the bladder, presumably due to plasma extravasation (C). In particular, the 170-kDa A1-I3 band was significantly increased (D). * = p < 0.05; ** = p < 0.01.

Back to article page

BMC Urology

ISSN: 1471-2490

Contact us