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Table 7 Median values and p-values between the 3 groups of increasing, stable or decreasing ANNV values

From: Artificial neural network (ANN) velocity better identifies benign prostatic hyperplasia but not prostate cancer compared with PSA velocity

 

Increasing ANNV (> 4)

Stable ANNV (-4 to 4)

Decreasing ANNV (< -4)

Parameter

PCa (n = 22)

BPH (n = 16)

p-value

PCa (n = 17)

BPH (n = 124)

p-value

PCa (n = 10)

BPH (n = 10)

p-value

Age (years)

65*

68.5

0.61

70

68

0.7

62

64

0.29

tPSA (ng/mL)

8.3

6.8

0.17

10.2

5.3

0.002

5.5

4.35

0.5

%fPSA (%)

8.0*$

13.15

0.017

15.15

17.4

0.85

11.2

13.8

0.1

Volume (mL)

33.5*

36.5*

0.34

50

53.5$

0.87

30.5*

34*

0.26

  1. The p-value is given for the comparison between the respective PCa and BPH patients (Mann-Whitney U Test)
  2. *significantly different to the respective patients in the stable group (P < 0.05; Mann-Whitney U Test)
  3. §significantly different to the respective patients in the decreasing group (P < 0.05; Mann-Whitney U Test)
  4. The Kruskal-Wallis Test for the PCa patients between all 3 groups showed only for %fPSA (p = 0.014) significant differences but not for age (p = 0.32), tPSA (p = 0.16) or volume (p = 0.98).
  5. The Kruskal-Wallis Test for the BPH patients between all 3 groups showed for volume (p = 0.022) significant differences but not for age (p = 0.31), tPSA (p = 0.61) or %fPSA (p = 0.17).