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Table 3 Multivariate survival analysis of interactions between clinicopathological variables and cancer specific survival in 196 patients operated with radical nephrectomy for renal cell carcinoma.

From: The prognostic relevance of interactions between venous invasion, lymph node involvement and distant metastases in renal cell carcinoma after radical nephrectomy

MULTIVARIATE

Cancer specific survival

 

ANALYSES

HR

95% CI

p-value

Lymph Node Involvement present

   

   VI present, SDM present

0.55

0.23 – 1.30

0.173

   VI present, SDM absent

2.78

0.80 – 9.64

0.108

   VI absent, SDM present

1.77

0.74 – 4.21

0.197

   VI absent, SDM absent

8.96

3.27 – 24.56

<0.001

Venous invasion present

   

   LNI present

0.63

0.25 – 1.64

0.349

   LNI absent

2.05

1.22 – 3.43

0.006

Synchronous distant metastases present

   

LNI present

0.93

0.32 – 2.74

0.894

LNI absent

4.71

2.68 – 8.27

<0.001

CCTS (Tumour size per 10 cm)

1.49

0.75 – 2.95

0.256

ESR (≥ 28 mm vs. <28 mm ref.)

1.94

1.15 – 3.26

0.012

ECOG PS (≥ 1 vs. 0)

1.47

0.93 – 2.33

0.099

Mode of detection (Symptomatic vs. Incidental)

0.66

0.25 – 1.71

0.392