Table 1 Clinical characteristics' of patients undergoing immunohistochemical analysis and the difference in various parameters between IHC expressed (+ve) and those that did not express IHC markers (-ve)
CgA+ve n = 30 | CgA -ve n = 54 | p value | NSE +ve n = 44 | NSE -ve n = 40 | p value | SYN +ve n = 8 | SYN -ve n = 76 | p value | |
|---|---|---|---|---|---|---|---|---|---|
Age (median ±) | 73.2 ± 6.3 | 69.1 ± 7.4 | 0.22 | 70.3 ± 7.4 | 68.4 ± 7.1 | 0.33 | 70.9 ± 9 | 71.2 ± 8.1 | 0.20 |
PSA mean (ng/ml) | 432 | 310 | 0.10 | 606 | 444 | 0.10 | 112 | 412 | 0.01 |
Clinical stage Organ Confined | 5 | 12 | 0.03 | 12 | 5 | 0.02 | 2 | 15 | 0.001 |
Locally Advanced | 8 | 27 | 0.02 | 12 | 23 | 0.05 | 3 | 32 | 0.001 |
Metastatic | 17 | 26 | 0.10 | 20 | 23 | 0.32 | 3 | 40 | 0.001 |
Gleason sum (mean) | 6.9 | 6.1 | 0.05 | 6.1 | 7.2 | 0.04 | 7 | 6.3 | 0.22 |