Table 2 Therapeutic modulation of PRV-associated pelvic pain.
From: Pharmacologic attenuation of pelvic pain in a murine model of interstitial cystitis
Group | % Increase* | % Relief** | P-Value** |
|---|---|---|---|
Experiment 1 | Â | Â | Â |
   Saline | 392.4 ± 39.6 | 0 |  |
   Hydroxyzine | 383.9 ± 123.9 | 2 | P < 0.96 |
   Diphenhydramine | 222.4 ± 74.7 | 44 | P < 0.08 |
   Cetirizine | 230.6 ± 52.8 | 41 | P < 0.06 |
Experiment 2 | Â | Â | Â |
   Saline | 431.7 ± 92.4 | 0 |  |
   Cimetidine | 182.4 ± 43.3 | 58 | P < 0.02 |
   Ranitidine | 101.0 ± 37.5 | 77 | P < 0.005 |
   Famotidine | 167.3 ± 35.1 | 61 | P < 0.02 |
Experiment 3 | Â | Â | Â |
   Saline | 498.8 ± 112.7 | 0 |  |
   Gabapentin | 371.7 ± 136.7 | 25 | P < 0.50 |
   L-703,606 | 116.7 ± 55.8 | 77 | P < 0.02 |
Experiment 4 | Â | Â | Â |
   Saline | 388.1 ± 69.5 | 0 |  |
   Lansoprazole | 394.0 ± 44.7 | 0 | P < 0.95 |
   Omeprazole | 368.7 ± 68.6 | 5 | P < 0.85 |
   Imetit | 454.3 ± 111.8 | 0 | P < 0.63 |