From: Focal therapy for prostate cancer: revolution or evolution?
Serum PSA | PSA < 10 ng/mL, PSAD < 0.15 ng/mL/g |
Clinical Stage | T1NxMx or T2aNxMx |
Pathologic evaluation/Gleason score^ | 3+3 or less (no grade 4 or 5) |
 | No more than 2 adjacent regions positive for cancer |
 | Total length of cancer < 10 mm total and < 7 mm in any 1 core; < 1/3 of cores positive for cancer |
Radiologic Imaging (MRI +/- MRSI) | Largest dimension < 15 mm if prostate volume > 25 grams or < 10 mm if volume < 25 grams. Capsular contact < 5 mm on axial imaging. No signs of extracapsular extension or seminal vesicle invasion |