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Table 2 Detection rates of prostate cancer in men with HGPIN based on the baseline PSA level at first biopsy

From: Risk of prostate cancer after detection of isolated high-grade prostatic intraepithelial neoplasia (HGPIN) on extended core needle biopsy: a UK hospital experience

PSA range (ng/ml)

Mean PSA in ng/ml (range)

No. men with HGPIN

Mean age [y (range)]

No. undergoing repeat biopsies

CaP diagnosis

Percentage with CaP diagnosis†

≤ 5

3.3

(1.5 to 5)

15

61.7

(52 to 74)

9

1

11

> 5 ≤ 10

7.1

(5.2 to 9.5)

37

65.4

(52 to 81)

32

11

34

> 10 ≤ 20

13.5

(10.1 to 19.7)

28

70.1

(61 to 86)

18

9

50

> 20

34.5

(21.3 to 68.2)

8

73.7

(62 to 84)

8

7

87.5

  1. Calculated as a percentage of those that underwent repeat biopsies and were subsequently detected with CaP