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Table 3 Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and 95% confidence intervals (CI) at different risk score cut points, Hospital (1) sample

From: Development and validation of risk score for predicting positive repeat prostate biopsy in patients with a previous negative biopsy in a UK population

Risk score cut point

Sensitivity

Specificity

PPV

NPV

  

95% CI

 

%

95% CI

 

%

95% CI

 

%

95% CI

 

> 0.1

90.0

68.3

98.8

38.1

23.6

54.4

40.9

26.3

56.8

88.9

65.3

98.6

> 0.2

90.0

68.3

98.8

52.4

36.4

68

47.4

31.0

64.2

91.7

73.0

99

> 0.3

75.0

50.9

91.3

71.4

55.4

84.3

55.6

35.3

74.5

85.7

69.7

95.2

> 0.4

70.0

45.7

88.1

83.3

68.6

93.0

66.7

43.0

85.4

85.4

70.8

94.4

> 0.45

65.0

40.8

84.6

85.7

71.5

94.6

68.4

43.4

87.4

83.7

69.3

93.2

> 0.5

55.0

31.5

76.9

88.1

74.4

96.0

68.8

41.3

89.0

80.4

66.1

90.6

> 0.6

35.0

15.4

59.2

95.2

83.8

99.4

77.8

40.0

97.2

75.5

61.7

86.2

> 0.7

10.0

1.2

31.7

97.6

87.4

99.9

66.7

9.4

99.2

69.5

56.1

80.8

> 0.8

0.0

0.0

16.8

97.6

87.4

99.9

0.0

0.0

97.5

67.2

54.0

78.7