Targeted salvage lymphadenectomy in patients treated with radical prostatectomy with biochemical recurrence: complete biochemical response without adjuvant therapy in patients with low volume lymph node recurrence over a long-term follow-up

Table 1 Summary of patient characteristics and PSA outcome after secondary resection of lymph node metastases without adjuvant therapy

Patient	Age (yr)	Primary treatment	Initial tumour stage	Gleason score	Hormonal therapy after primary treatment	Radio-therapy after primary treatment	PSA initial (ng/ml)	PSA1 (ng/ml)	[11C] choline PET/CT	[18F]fluoro-ethylcholine PET/CT	PET/CT positive LN	PSA2 (ng/ml)	Follow-up (month)
1	61	RRP + PLND	pT3a pN0 M0 R0	3 + 4	-	-	4.13	0.92	+	-	1	0.22	79
2	59	RRP + PLND	pT2c pN0 M0 R0	4 + 3	+	-	26.7	4.09	+	-	1	<0.01	83
3	64	RRP + PLND	pT3a pN1 M0 R0	4 + 3	-	-	16.0	2.45	+	-	1	<0.01	72
4	68	RRP	pT3a pNx M0 R0	-	-	+	9.9	1.64	-	+	1	<0.01	37
5	78	RRP + PLND	pT3b pN0 M0 R0	3 + 4	-	-	3.2	1.62	+	-	1	2.7	27
6	59	RRP + PLND	pT3a pN0 M0 R0	4 + 3	+	-	7.6	4.51	+	-	1	1.5	6
7	49	RRP + PLND	pT3b pN0 M0 R0	4 + 5	-	-	4.0	0.67	+	-	1	0.03	5
8	61	RRP + PLND	pT3a pN0 M0 R0	5 + 5	+	+	NA	9.55	+	-	3	54.46	12
9	53	RRP + PLND	pT3a pN0 M0 R1	4 + 4	-	+	36.0	3.54	-	+	1	0.4	7
10	75	RRP + PLND	pT3a pN0 M0 R1	4 + 3	-	+	5.94	3.77	+	-	1	10.3	2
11	75	RRP + PLND	pT3a pN0 M0 R0	3 + 3	-	+	7.14	0.94	-	+	1	0.01	10
12	55	RRP + PLND	pT3b pN1 M0 R0	4 + 3	-	-	5.08	0.5	+	-	2	no histologically confirmed LNM
13	64	RRP + PLND	pT3a pN0 M0 R1	-	-	+	8.21	1.23	+	-	1	no histologically confirmed LNM
Median	61							1.64			1

RRP = radical retropubic prostatectomy; PLND = pelvic lymph node dissection; PSA initial = PSA at primary diagnosis; PSA1 = PSA at time of PET/CT diagnosis; PSA2 = PSA after resection of lymph node metastases; LNM = lymph node metastases. NA = not available.

ISSN: 1471-2490