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Figure 11 | BMC Urology

Figure 11

From: Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms

Figure 11

Urodynamic recordings from non-anesthetized rats upon intravesical instillation of low and high PDBu. A, Representative traces of intravesical pressure (top panel) and voided volume (lower panel) in rats instilled with low concentration of PDBu (50 nM). B, Representative traces of intravesical pressure (top panel) and voided volume (lower panel) in rats instilled with high concentration of PDBu (1 μM). C, Perfusion of the urinary bladder in vivo with low PDBu did not affect the voided volume (C) nor the number of voids (D). However, high concentration of PDBu caused a significant increase in the frequency of micturition contractions (B; upper panel), and a decrease in voided volume (B; lower panel) in unanesthetized rats.

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