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Figure 12 | BMC Urology

Figure 12

From: Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms

Figure 12

Urodynamic recordings showing the effect of PMA inhibitor, Ro318220, after intravesical instillation in vivo.A, Representative traces of intravesical pressure (top panel) and voided volume (lower panel) in a control rat instilled with saline. B, Representative traces of intravesical pressure (top panel) and voided volume (lower panel) in a rat instilled with Ro318220 (50 μM). C, Changes in voided volume after instillation with Ro318220. D, Number of non-voiding contractions after intravesical application of Ro318220 was increased from 2 ± 0.5 to 6 ± 1.1 over 1 h period. The decrease in voided volume was followed by a two-fold increase in frequency over the same time period (N = 4, p ≤ 0.05 to control group).

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BMC Urology

ISSN: 1471-2490

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