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Figure 2 | BMC Urology

Figure 2

From: Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms

Figure 2

Effects of PDBu, a PKC activator, on contractility responses of BSM to EFS in vitro. Muscle strips were pre-incubated for 30 minutes with different concentrations of PDBu (0.01-1 μM), followed by a number of increasing frequencies of EFS stimulations (0.5-32 Hz). A, Representative raw tracings for control (upper panel), and experimental (lower panels) groups treated with PDBu. B, Summarized peak amplitude of contractions (PF, N = 5, n = 8 for each concentration; p ≤ 0.05 at stimulations up to 4 Hz). C, PDBu caused a significant increase in IF at 0.5-4 Hz (N = 5,n = 8, p ≤ 0.05 to control values). The results were not significantly different at 8, 16, and 32 Hz for PF and IF.

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BMC Urology

ISSN: 1471-2490

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