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Figure 9 | BMC Urology

Figure 9

From: Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms

Figure 9

Effects of PKC inhibition by Bim-1 on carbachol dose-response curve. A, Raw tracers of contractile responses to increasing concentrations of carbachol in the control (top panel) strips, and strips pre-treated with Bim-1 (bottom panel). B, Bim-1 (28 nM) had no significant effect on either the sensitivity to muscarinic stimulation (EC 50), or the maximum contraction (PF) upon carbachol application (p = 0.061 for all concentrations of carbachol).

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