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Table 1 The 13 patient cohorts (N = 1454) included in BC-BET. The numbers in the table correspond to the number of patients with each clinical characteristic or available endpoint that are included in the database and analyzed. A ‘-’ denotes insufficient sample size for analysis

From: An online tool for evaluating diagnostic and prognostic gene expression biomarkers in bladder cancer

  

# of samples

Cohort (availability)*

Platform

Normal, Tumor

LG, HG

NMI, MI

DSS

OS

RFS

Total (N)

AUH-1 [27] (GSE3167)

Affymetrix Human Genome U133A

9,41

8, 32

28, 13

50

AUH-2 [28]

(GSE5479)

MDL Human 3 k

98, 271

351, 51

404

Blaveri [14] (S)

UCSF Human Array 2.0

10, 68

27, 53

74

74

CNUH [29] (GSE13507)

Illumina human-6 v2.0

10, 165

105, 60

104, 61

165

165

175

DFCI [30] (GSE31684)

Affymetrix Human Genome U133 Plus 2.0

6, 84

15, 78

90

93

Lindgren [31] (GSE19915)

Swegene

12,144

72, 72

97, 45

142

156

Lindgren-2 [32] (GSE32548)

Illumina HumanHT-12 V3.0

56, 75

92, 38

89

131

MDA-1 [33] (GSE48276)

Illumina HumanHT-12 WG-DASL V4.0 R2

22

22

MDA-2 [33] (GSE48075)

Illumina HumanHT-12 V3.0

67, 73

73

140

MSKCC [15] (S)

Affymetrix Human Genome U133A

38,91

18, 73

25, 66

87

129

UVA [34] (GSE37317)

Affymetrix Human Genome U133A

8, 10

18

Stransky-1 [35] (E-TABM-147)

Affymetrix Human Genome U95A

5,26

11, 15

9, 17

31

Stransky-2 [35] (E-TABM-147)

Affymetrix Human Genome U95Av2

13, 16

16, 15

31

Total

 

74, 467

397, 769

839, 523

252

565

90

1454

  1. *Gene expression data for all cohorts are publicly available from the Gene Expression Omnibus (GEO) [13] with the given Accession # (GSE ID), from Array Express [9] (Accession # E-TABM-147) or as Supplementary material to publication (S). patients have MI, HG tumors (MDA-1) or MI tumors with unspecified grade (MDA-2). Abbreviations: LG, low grade; HG, high grade; NMI, non-muscle invasive; MI, muscle-invasive; DSS, disease-specific survival; OS, overall survival; RFS, recurrence-free survival