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Table 1 Contemporary series of AIHA associated with renal tumor

From: Autoimmune hemolytic anemia associated with renal urothelial cancer: A case report and literature review

References

Age/Sex

Hb

Stage, Pathology

Cooms test (Direct/Indirect)

Treatment

Response to Treatment

Outcome

Pirofsky B (1968)

65/M

Ht:26%

non-metastatic

positive/positive

steroid

CR

NA

  

RCC

 

nephrectomy

  

Spira MA (1979)

68/F

8.7

hypernephroma

positive/positive

steroid

CR

recurrence-free RCC and

   

(IgG)

nephrectomy

 

AIHA for 5 years

    

splenectomy

  

Bradley G (1981)

57/F

6.8

non-metastatic

positive/positive

steroid

CR

died with lung metastasis after 17 months with AIHA

  

clear cell RCC

Non-specific

nephrectomy

 
   

(only IgG negative)

  

Venzano C (1985)

71/F

7.5

lymph-node metastasis,

positive/positive

steroid

CR

NA

  

renal cell carcinoma

    

Girelli G (1988)

39/M

4.0

T3b

positive/positive

steroid

CR

DAT remained positive, no follow-up data

  

clear cell RCC

(IgM)

nephrectomy

 

Monga M (1995)

38/F

 

T1N0M0

negative/positive

nephrectomy

CR

sustained CR of RCC and AIHA for 2+ years

  

renal cell cancer

   

Lands R (1996)

65/M

8.1

T3a

positive

steroid

CR

NA

  

adenocarcinoma

 

nephrectomy

  

Kamra D (2002)

68/F

5.6

T2N0M0

negative

steroid

CR

NA

  

clear cell RCC

 

globulin therapy

  
    

nephrectomy

  

Muñoz-Ibarrav EL (2013)

71/F

6.7

T1aN0M0

positive

steroid

  
  

clear cell RCC

 

nephrectomy

CR

NA

Our case (2015)

52/M

3.2

T4N2M0

positive/positive

steroid

CR

died with multiple metastases after 7 months without AIHA

  

UC+RCC

(IgG)

globulin therapy

 
     

nephrectomy