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Table 1 Patient data

From: Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle

No.

Age

Sex

Diagnosis and cystectomy indication

Type of surgery

History

1

68

m

Bladder cancer G2 pT2b pN0 (0/9) L0 F0 R0 cM0

Radical cystectomy/neobladder

S/P 1× TUR bladder G3 pT2a

2

66

w

Bladder cancer pT1 G3 pN0 L0 V0 R0 M0

Radical cystectomy/Mainz Pouch I

S/P 1× TUR bladder G2 pT1 and Cis

3

61

m

Bladder cancer pT3a pN0 cMx R0 G3 Carcinoma left renal pelvis pT2 pN3 cMx R1 G3 Prostate cancer pT1a pN0 cMx Gleason 2 + 3 = 5

Radical cystectomy and nephroureterectomy left/ileal conduit

S/P 11× TUR bladder G2 pTa and Cis, at least pT2 G3

4

80

m

Bladder cancer pT2b (is) pN0 cM0 R0 L0 V0 G3 Prostate cancer: pT2a pN0 (0/13) R0 L0 V0 Gleason: 3 + 3

Radical cystectomy/ileal conduit

S/P 1 × TUR bladder G3, pT2a

5

68

m

Bladder cancer pT1 (is) pN0 (0/12) G3 R0 L0 V0

Radical cystectomy/ileal conduit

S/P 1× TUR bladder pT1 G3 and pTa G2

6

62

m

Bladder cancer pT2b (is), pNo (0/20) G3 R0 L1 V0 cM0

Radical cystectomy/ileal conduit

S/P 1× TUR bladder pT2a G3

7

73

m

Bladder cancer (with adenoid vegetations) G3 pT1 pN0 (0/11) L0 V0 R0 M0 Prostate cancer G2 pT2c PN0 L0 V0 R0 M0 Gleason 3 + 2 = 5

Radical cystectomy/ileal conduit

S/P 1× TUR-prostate (no malignancy) S/P 1x TUR-bladder pT1 G3

8

46

m

Bladder cancer G2 pTa pN0 (0/18) L0 V0 R0 M0 and renal failure (on dialysis)

Radical cystectomy/ileal conduit

S/P 1× TUR-bladder (necrotic urothelial carcinoma)

9

84

w

Bladder cancer G4, pT4a pN0 (0/9) M1 (PER) L1 V0 R1 (with sarcomatoid differentiation)

Radical cystectomy with cutaneous ureterostomy

S/P 6× TUR-bladder rpTa-1 G1-2, at least G3 pT2

10

50

m

Prostate cancer 4 + 5 = 9; pT4 pN1 (8/22) L0 V0 R0 cM0 (with bladder infiltration)

Radical cystectomy/ileal conduit

S/P prostate biopsy pT1c Gleason 5 + 4 = 9 and suprapubic catheter after overflow bladder

11

60

m

Bladder cancer pT1 pN0 cM0 R0 G2 (high grade)

Radical cystectomy/ileal conduit

S/P 1× TUR bladder pTa G2 and pT1 G2

12

80

w

Bladder cancer pT1 pN0 cM0 R0 G2 (high grade)

Radical cystectomy with urethrectomy/ileal conduit

no history available

13

68

m

Neurogenic bladder (contracted bladder) Prostate cancer pT2c R0 L0 V0; Gleason 3 + 3 = 6

Radical cystectomy/ ileal conduit

Incomplete paraplegia Th4 Polyneuropathy due to alcoholism S/P suprapubic catheter

14

74

m

Bladder cancer pT1 pN2 (2/17) G3 R0 L1 V0

Radical cystectomy/ileal conduit

no history available

15

59

m

Bladder cancer pT3b pN2 (2/12) G3 R0 L1 V0

Radical cystectomy/neobladder

S/P 2× TUR-bladder pT1 G2-3 (adenocarcinoma)

16

60

m

Bladder cancer pTis pN0 (0/24) R0 M0 Renal pelvic cancer pT3 G2 R0 N0 L0 V0

Radical cystectomy/ileal conduit and left nephrectomy

S/P 1×TUR-bladder pTis with urothelial carcinoma G2-3 and urothelial carcinoma left renal pelvis G1 pTa

17

57

m

Bladder cancer G3 pT1 pN0 (0/26) L0 V0 R0 cM0

Radical cystectomy/neobladder

S/P 3× TUR-bladder G3, pTa and mrpTis

18

71

m

Bladder cancer G3 pT3b pN2 (9/20) L1 V1 R0 cM1

Radical cystectomy/ileal conduit

S/P 7× TUR-bladder pTa G2 and pT1G3 and rpT1G3

19

74

m

Bladder cancer G3 pT2a pN0 (0/5) L0 V0 R0 cM0 Prostate cancer pT2 pN0 M0 G2

Radical cystectomy/ ileal conduit

S/P 1× TUR-bladder mpT1 G3

20

72

m

Bladder cancer pTX pN2 (3/12) G3 R0 cM0

Radical cystectomy/ileal conduit

S/P TUR-bladder T2a G2-3

21

75

m

Bladder cancer G3 pT3b pN0 (0/14) L1 V0 R1 cM0 Prostate cancer Gleason: 4 + 5 = 9; G3 pT2c pN0 L0 V0

Radical cystectomy/ileal conduit

S/P 1× TUR-bladder T2 G3, renal failure

22

56

m

Bladder cancer G3 pT3a pN3 L1 V1 pM1 (LYM) Prostate cancer Gleason 2 + 3 = 5; G2 pT2c

Radical cystectomy/ileal conduit

S/P TUR-bladder T2 G3

23

77

m

Bladder cancer G3 pT1 pN0 (0/13) L0 V0 R0 cM0 Prostate cancer Gleason 3 + 4 = 7; G3 pT2a pN0 L0 V0 R0 M0

Radical cystectomy/ileal conduit

S/P 4× TUR-bladder rpT1G2 and pTa G2

24

84

m

Bladder cancer G3 pT2a pN0 (0/17) L0 V0 R0 cM0

Radical cystectomy/ileal conduit

S/P 3× TUR-bladder pTa G1-2 and at least pT2 G3

25

56

w

Bladder cancer pT1 (is) pN0 cM0 R0 G3 V0 L0

Radical cystectomy/Mainz Pouch I

S/P 1× TUR-bladder pT1 G3 and mpTis

26

80

w

Bladder cancer G3 pT1 (is) pN0 (0/21) Mx V0 L0 R0

Radical cystectomy/ileal conduit

S/P 1× TUR-bladder G3 pT1

27

55

w

Urethra cancer pT2 pN0 (0/22) G2 R0 L0 V0 cM0 (squamous cell carcinoma)

Radical cystectomy/Mainz Pouch I

S/P 1× TUR-urethra (squamous cell carcinoma pTis)

28

52

m

Bladder cancer pT3b pN2 (9/20) M1 (lymph) G3 R0 L1 V0 Prostate cancer pT2c pN0 cM0 R0 L0 V0 Gleason 3 + 4 = 7

Radical cystectomy/ileal conduit

S/P 1× TUR-bladder G3 pT2

29

56

m

Bladder cancer pT3a pN0 (0/25) G3 R0 L1 V0 cM0

Radical cystectomy/neobladder

S/P 1× TUR-bladder G3 pT2 (is)

30

56

m

Prostate cancer Gleason 4 (80 %) + 3 = 7; G3 pT4 pN1 (4/12) L1 V0 R1 cM0 (with bladder infiltration)

Radical cystectomy/ileal conduit

no history available

31

76

w

Bladder cancer pT3b pN1 (1/18) G3 R0 L1 V0 cM0

Radical cystectomy/ileal conduit

S/P 1× TUR-bladder pT2 G3 S/P TFS (tissue fixation system - sacrouterine ligament)

32

70

m

Bladder cancer G2 pT3b pN0 (0/15) MX V0 L0 R0 (squamous cell carcinoma)

Radical cystectomy/ileal conduit

S/P 1× TUR-bladder pT2 G3 (squamous cell carcinoma)

33

81

m

Bladder cancer ypTis pN0 (0/17) R0 cM0 Prostate cancer pT2a pN0 (0/17) R0 L0 V0, Gleason 3 + 3 = 6

Radical cystectomy/ileal conduit

S/P 1× TUR-bladder pT1 (m, is) G2-3

34

63

m

Cancer of prostatic duct

Radical cystectomy/ileal conduit

S/P mult. TUR-bladder (carcinoma in prostatic duct)

35

74

m

Bladder cancer pT1 pN0 cM0 R0 G2 V0 L0

Radical cystectomy/neobladder

S/P1× TUR-bladder at least pT1 G3

36

59

m

Bladder cancer G3 pT2(is) pN2 (3/25) pM1 (lymph) L1 V1 R0 Prostate adenocarcinoma G2, Gleason 3 + 3 = 6, pT2b pN0 L0 V0 Pn1 R0

Radical cystectomy/neobladder

S/P1× TUR-bladder mpT2 (is) L1 G2-3

37

76

m

Bladder cancer and prostate cancer pT2c pN0 (0/18) R0 L0 V0 pN0, Gleason: 3 + 3 = 6

Radical cystectomy/ileal conduit

no history available

38

68

w

Neurogenic bladder, multiple sclerosis

Cystectomy/ileal conduit

Chronic pelvic pain, detrusor hyperactivity, incomplete spastic paraplegia

39

51

m

Bladder cancer pT4a (is) pN0 (0/16) G3 R0 L1 V0 cM0

Radical cystectomy/ileal conduit

S/P 1× TUR-bladder G3, at least pT1 Nx M0 Nicotine abuse

40

84

m

Bladder cancer G3 pT3a (is) pN0 (0/11) L0 V1 R0 cM0 Prostate adenocarcinoma Gleason 4 + 4 = 8, G3 pT2c pN0 L0 V0 R0 cM0

Radical cystectomy/ileal conduit

no history available

41

74

m

Bladder cancer G3 pT1 pN0 (0/18) L0 V0 R0 M0

Radical cystectomy/ileal conduit

S/P G3, at least pT1 and carcinoma in situ.

  1. S/P status post, TUR transurethral resection