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Table 2 Baseline patient characteristics

From: Degarelix therapy for prostate cancer in a real-world setting: experience from the German IQUO (Association for Uro-Oncological Quality Assurance) Firmagon® registry

Characteristic

N = 1,010 (100)

Mean (SD) age,1 years

70.29 (8.55)

Mean (SD) BMI,1 kg/m2

26.88 (3.81)

Median (range) PSA ng/ml

14.27 (0–6131)

Median (range) testosterone ng/ml (n = 266)a

0.52 (0–34.45)

Testosterone categories n, % (n = 266)

 <0.1 ng/ml

26 (9.8)

 0.1– ≤ 0.2 ng/ml

54 (20.3)

 0.2–0.5 ng/ml

48 (18.1)

 > 0.5 ng/ml

138 (51.9)

Disease stage n (%)

 Localizedb

469 (46)

 Locally advancedc

201 (20)

 Metastaticd

340 (34)

Gleason score n, %

N = 868

 2–4

13 (1.5)

 5–6

130 (15.0)

 7

290 (33.4)

 8–10

416 (47.9)

 Not classified

19 (2.2)

PSA categories n, %

 < 10 ng/ml

438 (43.4)

 10– ≤ 20 ng/ml

133 (13.1)

 20–50 ng/ml

160 (15.8)

 > 50 ng/ml

279 (27.6)

Previous treatment

Watchful waiting (%)

 N

829 (82.1)

 Y

181 (17.9)

External radiotherapy (%)

 N

783 (77.5)

 Y

227 (22.5)

Brachytherapy (%)

 N

990 (98.0)

 Y

20 (2.0)

High-intensity focused ultrasound(%)

 N

1002 (99.2)

 Y

8 (0.8)

Radical prostatectomy (%)

 N

764 (75.6)

 Y

246 (24.4)

Hormone therapy (%)

 N

468 (46.3)

 Y

542 (53.7)

 LHRH agonists

309 (57.0)

 GnRH antagonist

146 (26.9)

 Antiandrogen

87 (16.1)

Palliative therapy (%)

 N

766 (75.8)

 Y

244 (24.2)

  1. Baseline is defined as the beginning of degarelix therapy. aDocumentation of the testosterone value was optional; bLocalized disease: T1/T2, NX or N0, and MX or M0; cLocally advanced disease: T3/T4, NX or N0, and MX or M0; dMetastatic disease: N1 or M1, any T
  2. 1Recorded at the time of initial diagnosis of PCa