Table 1 Baseline characteristics and outcomes of patients with renal angiomyolipomas
From: Treatment of renal angiomyolipoma: pooled analysis of individual patient data
Variables | Overall | Conservative treatment | Cryoablation | Embolisation | Radiofrequency ablation | Partial nephrectomy/ enucleation | Nephrectomy | P-value |
|---|---|---|---|---|---|---|---|---|
No. of patients | 441 | 32 | 19 | 128 | 6 | 163 | 93 | |
Age (years) | 51.5 ± 14.5 | 53.2 ± 15.0 | 53.6 ± 14.8 | 47.9 ± 14.7 | 60.4 ± 6.9 | 52.9 ± 13.7 | 52.4 ± 14.9 | 0.020 |
Females | 353 (80.4) | 24 (75.0) | 18 (94.7) | 103 (80.5) | 5 (80) | 129 (79.6) | 74 (79.6) | 0.494 |
Imaging method | <0.0001 | |||||||
US | 9 (9.4) | 3 (9.4) | 0 | 2 (1.6) | 0 | 2 (1.2) | 2 (2.2) | |
CT | 411 (93.6) | 26 (81.3) | 8 (42.1) | 125 (97.7) | 6 (100) | 160 (98.2) | 86 (94.5) | |
MRI | 8 (1.8) | 3 (9.4) | 0 | 1 (0.8) | 0 | 1 (0.6) | 3 (3.3) | |
CT/MRI | 11 (2.5) | 0 | 11 (57.9) | 0 | 0 | 0 | 0 | |
Tumour diameter (cm) | 6.5 ± 5.0 | 4.4 ± 5.1 | 2.6 ± 1.6 | 9.1 ± 4.8 | 3.9 ± 2.5 | 4.7 ± 4.1 | 7.6 ± 6.0 | <0.0001 |
Bleeding | 54 (12.2) | 4 (12.5) | 0 | 32 (25.0) | 0 | 7 (4.3) | 10 (10.8) | <0.0001 |
3-year survival | 97.9 % | 100 % | 94.7 % | 100 % | 100 % | 95.6 % | 98.4 % | 0.037 |
Reintervention | 41 (9.4) | 1 (3.1) | 0 | 38 (29.7) | 0 | 2 (1.2) | 0 | <0.0001 |
Surgery | 18 (4.1) | 0 | 0 | 17 (13.3) | 0 | 0 | 0 | <0.0001 |
3-year freedom from reintervention | 87.8 % | 96.9 % | 100 % | 63.5 % | 100 % | 98.2 % | 100 % | <0.0001 |