Table 1 Descriptive statistics of 523 patients with clinical high-risk prostate cancer treated with radical prostatectomy and pelvic node dissection
Overall | 1RF | 2RF | 3RF | p | |
|---|---|---|---|---|---|
No (%) | 523 | 411 (79.5) | 93 (18.0) | 13 (2.5) | |
Missing | 3 | ||||
Age,yr | |||||
Age,yr Median | 64.0 | 64.0 | 64.0 | 59 | 0.02 |
Range | 41.0:79.0 | 44.0:79.0 | 44.0:76.0 | 47.0:70.0 | |
PSA, ng/ml | |||||
Median | 21.0 | 15.7 | 30.0 | 31.7 | <0.001 |
Range | 1.7: 158.0 | 1.7:158.0 | 3.0:134.0 | 22.0:50.0 | |
Clinical stage | |||||
cT1 | 266 (51.5) | 246 (59.9) | 20 (21.5) | 0 (0) | <0.0001 |
cT2 | 193 (37.3) | 150 (36.5) | 39 (41.9) | 4 (30.8) | |
cT3 | 58 (11.2) | 15 (3.6) | 34 (36.6) | 9 (69.2) | |
Biopsy Gleason sum | |||||
<=7 | 267 (51.6) | 232 (56.4) | 35 (37.6) | 0 (0) | <0.0001 |
>7 | 250 (48.4) | 179 (43.6) | 58 (62.4) | 13 (100) | |
Specimen Gleason sum | |||||
<=7 | 301 (58.2) | 250 (60.8) | 50 (53.8) | 1 (7.7) | 0.0004 |
>7 | 216 (41.8) | 161 (39.2) | 43 (46.2) | 12 (92.3) | |
Surgical margin | |||||
R0 | 289 (55.9) | 244 (59.4) | 39 (41.9) | 6 (46.2) | 0.0072 |
R1 | 228 (44.1) | 167 (40.6) | 54 (58.1) | 7 (53.8) | |
Pathological stage | |||||
pT2 | 150 (29.0) | 134 (32.6) | 14 (15.1) | 2 (15.4) | 0.0007 |
pT3 | 366 (70.8) | 277 (67.4) | 78 (83.9) | 11 (84.6) | |
pT4 | 1 (0.2) | 0 (0) | 1 (1.1) | 0 (0) | |
Lymph node involvement | |||||
No | 444 (87.6) | 364 (90.8) | 72 (77.4) | 8 (61.5) | 0.0001 |
Yes | 63 (12.4) | 37 (9.2) | 21 (22.6) | 5 (38.5) |