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Table 1 Clinical characteristics of the study population

From: The diagnostic accuracy of urine-based tests for bladder cancer varies greatly by patient

 

Cytology cohort

UroVysion FISH cohort

Sample size

  

 Unique subjects

871

827

 Test-cystoscopy pairs

4023

1696

Age (years, median)

66 (IQR: 56–75)

67 (IQR: 56–76)

  < 40

34 (4 %)

29 (4 %)

 40–50

89 (10 %)

84 (10 %)

 50–60

162 (19 %)

152 (18 %)

 60–70

248 (29 %)

227 (27 %)

 70–80

222 (26 %)

217 (26 %)

  ≥ 80

113 (13 %)

118 (14 %)

Gender

  

 Male

540 (62 %)

488 (59 %)

 Female

328 (38 %)

339 (41 %)

Race

  

 White

668 (78 %)

648 (78 %)

 Black

157 (18 %)

154 (19 %)

 Other

26 (3 %)

25 (3 %)

Smoking status

  

 Current smoker

75 (9 %)

82 (10 %)

 Former smoker

403 (48 %)

407 (49 %)

 Never smoker

356 (43 %)

338 (41 %)

Indication for test

  

 Hematuria

415 (48 %)

368 (44 %)

 Urothelial carcinoma

331 (38 %)

322 (39 %)

 Other

125 (14 %)

137 (17 %)

Cystoscopy result

  

 Negative

2783 (69 %)

1324 (78 %)

 Positive

752 (19 %)

185 (11 %)

 Atypical/Suspicious

492 (12 %)

187 (11 %)

Urine test result

  

 Negative

1632 (41 %)

1210 (71 %)

 Positive

375 (9 %)

486 (29 %)

 Atypical/Suspicious

2016 (50 %)

-

  1. IQR interquartile range